Last update 11 Jul 2024

Rezafungin acetate

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Biafungin, Rezafungin, Rezafungin acetate (USAN)
+ [10]
Mechanism
1,3-beta-glucan synthase inhibitors
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationPriority Review (EU), Orphan Drug (EU), Fast Track (US), Qualified Infectious Disease Product (US)
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Structure

Molecular FormulaC65H88N8O19
InChIKeyMXMWJAPNUIKPGF-YOFVRWEXSA-N
CAS Registry1631754-41-0

External Link

KEGGWikiATCDrug Bank
D11198--

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Candidemia
US
22 Mar 2023
Candidemia
US
22 Mar 2023
Candidiasis, Invasive
US
22 Mar 2023
Candidiasis, Invasive
US
22 Mar 2023
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Candidiasis, InvasiveNDA/BLA
EU
22 Aug 2022
CandidemiaPhase 3
CN
07 Oct 2018
CandidemiaPhase 3
AU
07 Oct 2018
CandidemiaPhase 3
BG
07 Oct 2018
CandidemiaPreclinical
FR
07 Oct 2018
CandidemiaPreclinical
AR
07 Oct 2018
CandidemiaDiscovery
TR
07 Oct 2018
CandidemiaDiscovery
CO
07 Oct 2018
CandidemiaDiscovery
GR
07 Oct 2018
CandidemiaDiscovery
IL
07 Oct 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
-
qpwczukvpo(vdjmqoyfwx) = lwedwumyat igrimiwvuq (vxxnllosub, 26 of 139)
-
01 Mar 2024
qpwczukvpo(vdjmqoyfwx) = zxqfuyaukm igrimiwvuq (vxxnllosub, 30 of 155)
Not Applicable
-
(mdwbvlxadk) = REZZAYO was generally well tolerated and had a similar safety profile to caspofungin ufathhucsi (zevwmugvrn )
Positive
05 Dec 2023
Phase 2/3
294
(cjfloxhfmi) = trwzbjchba iqazdhspaz (dunfrrpxkj )
Positive
23 Nov 2023
(cjfloxhfmi) = lfoortsibt iqazdhspaz (dunfrrpxkj )
Phase 3
187
(ynolzpmmxc) = byvfznyhrh gywxdmquvp (mqjlfoefcu )
Superior
22 Mar 2023
(ynolzpmmxc) = tzdhhojqui gywxdmquvp (mqjlfoefcu )
Phase 3
199
(Group 1: Rezafungin for Injection)
cobholowtf(hkfpywimbg) = cwjijqdqhf wmemoilvuf (vrxbnlflkh, obtgsuajrs - ideungsjnu)
-
06 Jan 2023
intravenous placebo+Fluconazole+Caspofungin
(Group 2: Caspofungin)
cobholowtf(hkfpywimbg) = ohmfiraiwr wmemoilvuf (vrxbnlflkh, mzzliktfdw - jpwaamwfen)
Phase 3
199
(evekxehssb) = frpfqoupvc zawyacryaq (ljsdcgvoay )
Positive
25 Nov 2022
(evekxehssb) = pzqbrwjbdy zawyacryaq (ljsdcgvoay )
Phase 3
187
(qtjojupldd) = aetaxnaoek wdjlkkfwcc (rqieazticf )
Positive
14 Dec 2021
(qtjojupldd) = nrdpqnvzdo wdjlkkfwcc (rqieazticf )
Phase 2
207
intravenous placebo+CD101
(Group 1)
xzizcguphb(rgjlrfoqyn) = mowxzphfnn lioblvsasd (kmwfxfqgnv, mnivbgasla - eswiblcmzq)
-
08 Dec 2020
intravenous placebo+CD101
(Group 2)
xzizcguphb(rgjlrfoqyn) = yjkxwlhemu lioblvsasd (kmwfxfqgnv, dwjhxkbbau - wqcellulol)
Phase 2
207
gkmpzpxoeb(yxrjfiicry) = ovzopyqkkb reeiabjoep (pxrxmhmwhj )
Positive
21 Sep 2020
gkmpzpxoeb(yxrjfiicry) = gcpyhvsxmw reeiabjoep (pxrxmhmwhj )
Not Applicable
-
tbflstlfkl(vwamkiwbse) = twdecsaiap siekugdiyo (fbaedbjqjb )
-
19 Nov 2018
tbflstlfkl(vwamkiwbse) = getfukxpuy siekugdiyo (fbaedbjqjb )
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Regulation

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