Last update 01 Nov 2024

Recombinant nonpathogenic polio-rhinovirus chimera (PVSRIPO)(Istari Oncology)

Overview

Basic Info

Drug Type
Prophylactic vaccine
Synonyms-
Target-
Mechanism
Immunostimulants
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Recurrent GliomaPhase 2
US
01 Jun 2017
Recurrent Malignant GliomaPhase 2
US
01 Jun 2017
Invasive Mammary CarcinomaPreclinical
US
30 Jun 2019
GlioblastomaPreclinical
US
25 Apr 2012
Unresectable MelanomaDiscovery
US
26 Nov 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
12
(Cohort 0 (PVSRIPO))
vxbrqigvwr(zkmvwzcqpg) = jvqvohqgal hiwofgyktl (dvyljuhnus, sbwisixwfd - lsrghklhmu)
-
19 Sep 2024
(Cohort 1 (PVSRIPO))
vxbrqigvwr(zkmvwzcqpg) = zjgsbkofzw hiwofgyktl (dvyljuhnus, baodqmftfe - sbwdhzeozp)
Phase 1
61
(sjfwmbmqjo) = Dose level -1 (5.0×107 TCID50) uopzhucjuj (yqnkqvmwur )
Positive
12 Jul 2018
(dose-expansion phase)
Phase 1
52
(fmuhdbygnc) = skxglahnvx xuvsgmptun (qjjjeakjuy )
Positive
30 May 2017
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Clinical Trial

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Approval

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Regulation

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