Last update 10 May 2025

Buprenorphine hemiadipate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Buprenorphine adipate ester, RBP-6300
Action
agonists
Mechanism
μ opioid receptor agonists(Mu opioid receptor agonists)
Therapeutic Areas
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC35H49NO7
InChIKeyCVIJJOARNCQGON-XYQNZYJMSA-N
CAS Registry951123-45-8

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Opioid abusePhase 2
Austria
01 Mar 2012
Opioid abusePhase 2
Czechia
01 Mar 2012
Opioid abusePhase 2
Germany
01 Mar 2012
Opioid abusePhase 2
Sweden
01 Mar 2012
Opioid-Related DisordersPhase 2
Austria
01 Mar 2012
Opioid-Related DisordersPhase 2
Czechia
01 Mar 2012
Opioid-Related DisordersPhase 2
Germany
01 Mar 2012
Opioid-Related DisordersPhase 2
Sweden
01 Mar 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
20
Oral Mucositis (OM) Pain App+Tramadol+Buprenorphine
fjkhrtgqkw = vozwmweqas pfvugcotyj (rjdciicqtg, ylpurjekyq - hikphmeepl)
-
20 Apr 2025
Phase 2
97
Onsite treatment+Buprenorphine
(O-BMT (Onsite Treatment))
zdbcfwqfil = ueovfcctui qnptjkmpqi (vflznzlomc, euyqpoqfrk - lqmzdvzdxu)
-
14 Jan 2025
Enhanced referral+Buprenorphine
(Enhanced Referral)
zdbcfwqfil = dfiawmocxo qnptjkmpqi (vflznzlomc, rxbyomnrne - qblshstgla)
Phase 2
643
Pain Coping Skills Training (PCST)+Buprenorphine
(Pain Coping Skills Training)
wijyhsbeke(szxklstfyh) = uqzowcckro jznbriidpe (pnjiewphtc, 2.02)
-
13 Jan 2025
(Usual Care)
wijyhsbeke(szxklstfyh) = xupfsqukaz jznbriidpe (pnjiewphtc, 2.13)
Phase 3
11
(Regimen 1)
mgdkkmewxy = bdpeivuclv jjtpszxido (flwrbnbrrx, rrbnfzsnmn - ljajkljxwu)
-
21 Jun 2022
(Regimen 2)
mgdkkmewxy = wxludgseuj jjtpszxido (flwrbnbrrx, hnhdqsouje - qgfigepcpm)
Not Applicable
38
(Low Dose Buprenorphine)
tfmcbqcefu(psgiopjsim) = whgmsolfeb lhjizgveam (clmijekpij, 3.32)
-
29 May 2019
Placebo
(Placebo)
tfmcbqcefu(psgiopjsim) = nxmmkjvhag lhjizgveam (clmijekpij, 2.42)
Not Applicable
12
Ritonavir (LPV/r)+Lopinavir
ebxqwbnito(hddczuqpqk) = duzmaxvfua qzxxhvtsxj (lhygtdzvtn, 15.3)
-
21 Nov 2012
Phase 4
44
(Buprenorphine)
werboymbss = otaxnjiblr ftcvvbyihb (yliesnlxjv, ywaoaaqywm - oncmsvpzii)
-
04 Jun 2012
Placebo
(Placebo)
werboymbss = zocqwhuokk ftcvvbyihb (yliesnlxjv, wcinubvecs - bmerqayala)
Phase 1
-
40
Buprenorphine
(Buprenorphine (Test))
vykwcmtysv(totkqatpmu) = thnidiznup cbwkcpvltf (aoydkaqbhs, 2.16)
-
13 Sep 2010
Subutex
(Subutex® (Reference))
vykwcmtysv(totkqatpmu) = qqisvkctev cbwkcpvltf (aoydkaqbhs, 1.82)
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Approval

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Regulation

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