Last update 11 Jul 2024

DF-1001

Overview

Basic Info

Drug Type
Trispecific killer cell engager (TriKE)
Synonyms
Mechanism
CD16a antagonists(Low affinity immunoglobulin gamma Fc region receptor III-A antagonists), HER2 antagonists(Receptor protein-tyrosine kinase erbB-2 antagonists), NKG2D antagonists(NKG2-D type II integral membrane protein antagonists)
Therapeutic Areas
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
RegulationOrphan Drug (US)

R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
BE
11 Nov 2019
Advanced Malignant Solid NeoplasmPhase 2
FR
11 Nov 2019
Advanced Malignant Solid NeoplasmPhase 2
US
11 Nov 2019
Advanced Malignant Solid NeoplasmPhase 2
NL
11 Nov 2019
Advanced Malignant Solid NeoplasmPhase 2
DK
11 Nov 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
104
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Positive
31 May 2023
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Regulation

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