Last update 15 Sep 2023

Sovateltide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Sovatelitide, PMZ-1620, SPI-1620
+ [2]
Target
ETB(Endothelin receptor type B)
Mechanism
ETB agonists(Endothelin receptor type B agonists), Angiogenesis inducers, Neurogenesis stimulants
Therapeutic Areas
Nervous System Diseases, Endocrinology and Metabolic Disease, Cardiovascular Diseases+ [3]
Active Indication
Acute Ischemic Stroke, Alzheimer Disease, Cerebral Infarction+ [8]
Inactive Indication
Biliary Tract Neoplasms, Carcinoma, Non-Small Cell Lung Cancer
Originator Organization
Active Organization
Highest Phase (Global)Approved
First Approval Date(Global)
IN (May 2023),
Acute Ischemic Stroke
Regulation-
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Structure

Molecular FormulaC86H117N17O27
InChIKeyDXPHNGAMYPPTBJ-TZMIJSMNSA-N
CAS Registry142569-99-1

External Link

KEGGWikiATCDrug Bank
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R&D Status

IndicationHighest PhaseCountry/LocationOrganization
Acute Ischemic StrokeApprovedIN
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Alzheimer DiseasePhase 3 ClinicalIN
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Hypoxia-Ischemia, BrainPhase 2 ClinicalIN
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AsphyxiaPhase 2 ClinicalUS
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Biliary Tract NeoplasmsDiscontinuedUS
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Clinical Trial Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
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-
29 Jun 2012
Vehicle
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Phase 3
-
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-
28 Oct 2011
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Approval

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Regulation

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