Last update 07 Nov 2024

[68Ga]FAPI-46

Overview

Basic Info

Drug Type
Diagnostic radiopharmaceuticals, Radionuclide Drug Conjugates (RDC)
Synonyms
68 Ga FAPI 46, [68Ga]Ga-FAPI-46, 68Ga FAPI-46
+ [1]
Target
Mechanism
FAP antagonists(Fibroblast activation protein alpha antagonists), PET imaging(Positron-emission tomography enhancers)
Inactive Indication-
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)
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Structure

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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ovarian CancerPhase 2
DK
07 Jun 2024
Colitis, UlcerativePhase 2
NL
31 Aug 2023
Crohn DiseasePhase 2
NL
31 Aug 2023
FibrosisPhase 2
NL
31 Aug 2023
Gastrooesophageal junction cancerPhase 2-12 Jun 2023
Adenomatous Polyposis ColiPhase 2
US
02 May 2022
Pancreatic Ductal AdenocarcinomaPhase 2
US
02 May 2022
Alveolitis, Extrinsic AllergicPhase 1
US
16 Nov 2021
Idiopathic Interstitial PneumoniasPhase 1
US
16 Nov 2021
PneumoconiosisPhase 1
US
16 Nov 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
[18F]F-FAPI-74 PET/CT
ezjstbajoz(cokxnqscrp) = djurovyxit sbxijfmbai (vnmhkccmyg )
-
09 Jun 2024
Not Applicable
-
-
dslneazrdh(ztswpncuxr) = mayrqjgkwt ummfvpfqap (hgfjzchvhn )
-
28 Aug 2023
Not Applicable
-
-
(18F-FDG-PET)
vkbhunfqlw(olyyywsmze) = the average 68Ga-FAPI-46/18-FDG average ratio was higher in LC than in benign lesions (3.64 +/- 1.59 versus 1.89 +/- 0.32) hebtmwrnph (rvbrzgvwkm )
-
28 Aug 2023
Phase 2
91
(18F-FDG PET/CT)
gsgiwlxutb(evzktqlqty) = dwfptcsooc shduvuzlvb (ebvogyovtg )
Positive
28 Aug 2023
Not Applicable
-
-
atjoocpmxq(eryhianetc) = uhdzyanrxi bsaijaczlm (yngxfztnjo )
-
28 Aug 2023
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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