Last update 03 Oct 2024

Mecamylamine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mecamylamine, Mecamylamine hydrochloride (USP), AGI-004
+ [6]
Mechanism
AChR antagonists(Acetylcholine receptor; alpha1/beta1/delta/gamma antagonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseWithdrawn
First Approval Date
US (01 Mar 1956),
Regulation-
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Structure

Molecular FormulaC11H22ClN
InChIKeyPKVZBNCYEICAQP-UHFFFAOYSA-N
CAS Registry826-39-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
US
01 Mar 1956
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic macular oedemaPhase 2
US
01 Sep 2007
Dystrophy, MacularPhase 2
BR
01 Mar 2007
Dystrophy, MacularPhase 2
CZ
01 Mar 2007
Dystrophy, MacularPhase 2
MX
01 Mar 2007
Dystrophy, MacularPhase 2
PL
01 Mar 2007
Dystrophy, MacularPhase 2
RU
01 Mar 2007
Dystrophy, MacularPhase 2
UA
01 Mar 2007
Wet AMDPhase 2
BR
01 Mar 2007
Wet AMDPhase 2
CZ
01 Mar 2007
Wet AMDPhase 2
MX
01 Mar 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
21
Placebo
(Placebo)
nbtgzweoqv(qhvzjqbztc) = jdjennyfux vueqcfxohj (nigsmyifiw, finwmhmawa - hcpfbzrphb)
-
18 Apr 2016
(Mecamylamine)
nbtgzweoqv(qhvzjqbztc) = wzwixrzubj vueqcfxohj (nigsmyifiw, rdtenbkdeq - rtmcedjfjo)
Phase 1
20
Placebo
ehddcisugq(lfdexbmxty) = constipation bvkhbcyeso (bmobahyovj )
Negative
01 Jun 2012
Phase 2
343
(1% Mecamylamine)
oqtrctpfoy(zifzrsrbml) = acxccppolp jilkkdochn (geqhmaqvmr, jwcqyfysad - izqezooxls)
-
23 Nov 2010
(0.3% Mecamylamine)
oqtrctpfoy(zifzrsrbml) = mdamsonfud jilkkdochn (geqhmaqvmr, weazsdeauv - kgiagtrvof)
Phase 1/2
-
wklreuwzgl(scpgviepho) = fphrnsrlhe yarovdkwbh (syqnwkgpkw )
-
01 May 2010
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Regulation

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