Last update 20 Mar 2025

ASN-007

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
+ [1]
Action
inhibitors
Mechanism
ERK1 inhibitors(Extracellular-signal-regulated kinase1 inhibitors), ERK2 inhibitors(Extracellular-signal-regulated kinase 2 inhibitors)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Colorectal CarcinomaPhase 2
United States
20 Sep 2021
Metastatic Pancreatic Ductal AdenocarcinomaPhase 2
United States
20 Sep 2021
Advanced Malignant Solid NeoplasmPhase 2
United States
07 May 2021
Metastatic Solid TumorPhase 2
United States
07 May 2021
Gastrointestinal NeoplasmsPhase 2
United States
-
Acute Myeloid LeukemiaDiscovery
United States
15 Mar 2022
Metastatic colon cancerDiscovery
United States
19 Jan 2018
Metastatic melanomaDiscovery
United States
19 Jan 2018
metastatic non-small cell lung cancerDiscovery
United States
19 Jan 2018
Secondary malignant neoplasm of lungDiscovery
United States
19 Jan 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
19
djansctebw(yxvlthzsdh) = 26.3% koyhuxqmny (scdzdwfyav )
Positive
24 May 2024
Phase 1/2
12
(egadpjyhik) = xvviymhvfw gamfritntt (uniyuxjvms )
Positive
31 May 2023
Phase 1/2
30
(gfymtckmao) = cjwkcsgifl fouxrnpzqw (vtdfzrvbyg )
Positive
26 May 2023
Phase 1/2
-
(opkmjcyzun) = Monitorable and manageable adverse event (AE) profile with mostly grade 1 and 2 treatment-related AEs oznuicycfn (lpxbwehdtd )
Positive
12 Oct 2022
Phase 1
RAS/RAF mutation Solid Tumors
RAS Mutation | RAF Mutation | MEK Mutation
-
(yzqsqjbqno) = 40mg QD and 250mg QW,respectively hymsmafwwo (beixhxvite )
Positive
01 Dec 2019
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Approval

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Regulation

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