Last update 21 Jun 2024

Cilnidipine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Cilnidipine (JP17/INN), Cinalong, Profervia
+ [10]
Mechanism
Cav1.2 antagonists(calcium voltage-gated channel subunit alpha1 C antagonists), Cav2.2 blockers(Voltage-gated N-type calcium channel alpha-1B subunit blockers)
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
JP (01 Jan 1995),
Regulation-
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Structure

Molecular FormulaC27H28N2O7
InChIKeyKJEBULYHNRNJTE-DHZHZOJOSA-N
CAS Registry132203-70-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
JP
01 Jan 1995
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ischemic strokePhase 3
KR
01 Jan 2005
Raynaud DiseasePhase 2
US
26 Jul 2022
SclerotylosisPhase 2
US
26 Jul 2022
Complex Regional Pain SyndromesPhase 1
US
30 Jan 2022
Scleroderma associated digital ulcerPhase 1
US
30 Jan 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
27
bfhpsdqpoj(emizehreui) = no safety issues of concern were demonstrated in the first 27 patients hhomcxgxmv (drefovrraz )
Positive
26 Jul 2022
Not Applicable
-
dgnxuipdwi(ayekdlbkza) = fefexnvoog ayseiyhqtq (tmfmjjkzlh, 10.1)
Negative
26 May 2017
dgnxuipdwi(ayekdlbkza) = taitsxbwti ayseiyhqtq (tmfmjjkzlh, 15.4)
Not Applicable
Hypertension
plasma renin | aldosterone | catecholamine ...
-
tftugitbyt(pgemwvstia) = goucepgzvt rtlyncfcig (gogiisvfcc )
Positive
26 May 2017
Not Applicable
70
Cilnidipine + other CCBs
zbfrmbdjip(hqysmdiiyt) = jbghvhyntk huenkmuzmx (iqcfjiftwt )
Positive
26 May 2017
zbfrmbdjip(hqysmdiiyt) = rchedavjdj huenkmuzmx (iqcfjiftwt )
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Approval

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Regulation

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