Sclerotylosis

Using the marketed Bosentan Tablets (Quankeli) as the reference preparation, healthy Chinese male subjects were selected to conduct a comparative bioavailability study of a single oral dose of Bosentan Tablets produced by Xinchang Pharmaceutical Factory of Zhejiang Medicine Co., Ltd., under fasting and postprandial conditions, respectively, to evaluate the bioequivalence of the two Bosentan tablets in humans, and to provide a basis for the registration of Bosentan Tablets with my country's Food and Drug Administration and clinical use.

Using the marketed Bosentan Tablets (Quankeli) as the reference preparation, a single-dose oral bioavailability comparison study of Bosentan Tablets produced by Xinchang Pharmaceutical Factory of Zhejiang Medicine Co., Ltd. was conducted on healthy male subjects in China to evaluate the bioequivalence of the two Bosentan tablets in humans, and to provide a basis for the registration of Bosentan Tablets with my country's Food and Drug Administration and clinical use.

To study the relative bioavailability of a single intramuscular injection of compound betamethasone injection developed by Chongqing Huabang Pharmaceutical Co., Ltd. and compound betamethasone injection (Diprosone) produced by Shanghai Schering-Plough Pharmaceutical Co., Ltd. in healthy Chinese adult male volunteers, and to evaluate the bioequivalence of the test preparation and the reference preparation.