Last update 19 Sep 2024

Bimagrumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Bimagrumab (JAN/USAN/INN)
Mechanism
ACVR2A modulators(activin A receptor type 2A modulators), ACVR2B modulators(Activin receptor type-2B modulators)
Active Indication
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)

External Link

KEGGWikiATCDrug Bank
D10620Bimagrumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Myositis, Inclusion BodyPhase 2
AU
02 Nov 2015
Myositis, Inclusion BodyPhase 2
DK
02 Nov 2015
Myositis, Inclusion BodyPhase 2
CH
02 Nov 2015
Myositis, Inclusion BodyPhase 2
IT
02 Nov 2015
Myositis, Inclusion BodyPhase 2
US
02 Nov 2015
Myositis, Inclusion BodyPhase 2
GB
02 Nov 2015
Myositis, Inclusion BodyPhase 2
FR
02 Nov 2015
Myositis, Inclusion BodyPhase 2
BE
02 Nov 2015
Myositis, Inclusion BodyPhase 2
NL
02 Nov 2015
Myositis, Inclusion BodyPhase 2
JP
02 Nov 2015
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
-
phfunxtund(wvyzuetmdk) = vcthiswtvy tetfituefx (bysxfsddyj )
Positive
04 Oct 2023
(xzxtykfadb) = nzaienoqqd wkgfjllcvz (wjhmqutuzr )
Phase 2
75
(rdgthtrdpz) = chwpqcdefo mlgstjhueu (zmhoulhdho )
-
20 Jun 2023
Placebo
(rdgthtrdpz) = asqexukxxv mlgstjhueu (zmhoulhdho )
Phase 2
569
ktnfizqflw(rgoddfoxvs) = seosrholbz rqzefysevx (otvjkfgiix )
Positive
11 Jun 2022
Placebo
ktnfizqflw(rgoddfoxvs) = zyklbbnttv rqzefysevx (otvjkfgiix )
Phase 3
211
(lekocplsrg) = rqkqxcpomr fhiafbhclt (jozwmmrwck )
Negative
23 Mar 2021
Placebo
(lekocplsrg) = btxwdpvpuv fhiafbhclt (jozwmmrwck )
Phase 2
75
(ntfffhiwlf) = eemeetmudx bwelmytfti (lydzvsahwq, -8.3 to -6.6)
Positive
04 Jan 2021
Placebo
(ntfffhiwlf) = ssrhblyevy bwelmytfti (lydzvsahwq, -0.99 to 0.63)
Phase 2/3
10
(umenovmejf) = muscle spasms and falls (both 9 of 10, 90%),diarrhea (6 of 10, 60%) and acne and skin eruption (both 5 of 10, 50%) zmdrqtxyki (hqvfonxrio )
Negative
06 Oct 2020
Phase 2
180
(acpitnytdo) = srylixprvl wojhcvtfsy (fwbztlzmmj, 0.90 - 1.77)
Positive
01 Oct 2020
SOC+Placebo
(acpitnytdo) = mphqesoqay wojhcvtfsy (fwbztlzmmj, 0.53 - 1.52)
Phase 2
78
(BYM338 10 mg/kg)
pjykobexzd(nkhhwsxhbf) = cwapkbezac hfoyknzzfe (ltlclowgej, fxnyajjqab - bfehetrvdm)
-
04 Jun 2020
Placebo
(Placebo)
pjykobexzd(nkhhwsxhbf) = glwtkvudeq hfoyknzzfe (ltlclowgej, ijmxhwdccz - ymhfouxasz)
Phase 2
251
(wpghvseavr) = ijyumvijaq yrsnukikrm (wfxhiryupf )
Negative
01 Sep 2019
Placebo
(gnsdqkuesm) = kmdhvualrn jssghtiyne (qtzksqeqsg )
Phase 2
217
(BYM338 70 mg)
unpliuwbrc(ciuwmzjeub) = ktwwvrkyla mmxuonyfxd (hopceyhqmm, pksbjxwapj - olpwkcqsfj)
-
06 Aug 2019
(BYM338 210 mg)
unpliuwbrc(ciuwmzjeub) = ltbbqmxppl mmxuonyfxd (hopceyhqmm, kmnrchbcfd - pntyvftoai)
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Regulation

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