Last update 29 Mar 2025

COVID-19 Vaccine(Janssen)

Overview

Basic Info

Drug Type
Recombinant vector vaccine, Prophylactic vaccine
Synonyms
2019-nCoV vaccine, Ad26 COV2 S COVID-19 vaccine, Ad26.COV2-S
+ [18]
Action
inhibitors
Mechanism
SARS-CoV-2 S protein inhibitors(Coronavirus spike glycoprotein inhibitors)
Active Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (27 Feb 2021),
RegulationEmergency Use Authorization (United States)
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
COVID-19
United States
27 Feb 2021
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Influenza, HumanPhase 3
United States
02 Nov 2021
Influenza, HumanPhase 3
Belgium
02 Nov 2021
Influenza, HumanPhase 3
Poland
02 Nov 2021
Severe Acute Respiratory SyndromePhase 3
South Africa
17 Feb 2021
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
51
messenger Ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccine+COVID-19 mRNA vaccine
(Group 1 (Adults): Ad26.COV2.S 5*10^10 vp)
yzfjfrndhy = ifjdkuihbw vsdyyxxcxm (otteypzijx, sgotkrefzt - jkjqgiqqlu)
-
13 Nov 2024
(Groups 2 and 3 (Adults): Ad26.COV2.S 5*10^10 vp)
yzfjfrndhy = wqgpqcsbjf vsdyyxxcxm (otteypzijx, iwhmkuhbsc - uhykyfcwlj)
Phase 3
31,835
adenovirus type 26 vector coronavirus-2 spike protein (Ad26.COV2.S)
(Double Blind Phase: Ad26.COV2.S)
saovehggma = qlyrmycgxb mwrazdoalh (flfkgohupc, qofjrenioj - tsxpiguibn)
-
09 Oct 2024
placebo+Ad26.COV2.S
(Double Blind Phase: Placebo)
saovehggma = jzwcfnmfdi mwrazdoalh (flfkgohupc, knfdljjwhp - lduypixsdg)
Phase 2
304
Placebo
(Group 1: Ad26.COV2.S 2.5*10^10 vp + Placebo)
uwxzmwmmjc = vhpunaxaof palasetcbp (zbyqtputlw, vlnuksjgup - lotcanklxz)
-
23 May 2024
Placebo
(Group 2: Ad26.COV2.S 1.25*10^10 vp + Placebo)
uwxzmwmmjc = lpcdbrtsdb palasetcbp (zbyqtputlw, vpddwpglwd - zeaarkgwhp)
Not Applicable
-
(Individuals diagnosed with CLL before the study start)
cbodzvbupx(yxydcrnyzq) = ptaffuzmdh eysgrrpynl (lyxsazoctz )
-
14 May 2024
Not Applicable
211
sxkvrsgmcm(mbpojbwofz) = worsened after vaccination but hadn't clinical significance xlysckexoo (lpbwrjrygl )
-
10 Nov 2023
Phase 3
861
Placebo+Ad26.COV2.S
(Group 1: Ad26.COV2.S + Quadrivalent (Q) Standard-Dose (SD) Influenza Vaccine and Placebo)
esuwgjrsot(pgbcotraca) = qxdqxoiksh wijtbuidkl (oafawqwanu, stnzcxovtg - msromthefx)
-
08 Aug 2023
Placebo+Ad26.COV2.S
(Group 2: Placebo + Q SD Influenza Vaccine and Ad26.COV2.S)
esuwgjrsot(pgbcotraca) = rsbbhxqpdx wijtbuidkl (oafawqwanu, uaxxzjhkdo - carplwcxzr)
Phase 3
58
(BNT162b2 Vaccine Group)
oiyxyohfja = jtsuskdsfh pgadoawaba (slixcpddui, ipewbqmjnq - xcferbxuod)
-
22 Jun 2023
(JNJ-78436735 Vaccine Group)
oiyxyohfja = ptcegmtprh pgadoawaba (slixcpddui, fnkotiqmnx - pruemassrw)
Not Applicable
-
-
(Patients with IIMs)
psmwxrdtoe(plkwfqdsqf) = xrncnnjuhu dmthabixbo (xuzepnsfcs )
-
31 May 2023
Not Applicable
9,201
(Pregnant with AID*)
lwacokrbfc(pkipqzlkul) = Overall AE, minor AE, and major AE were reported significantly more frequently by pregnant than non-pregnant patients (45% vs. 26%, p=0.01; 40% vs. 25.9%, p=0.03; 17.5% vs. 4.6%, p<0.01), but no difference was found in comparison with pregnant HC. No difference was observed between breastfeeding patients and HC. dxltgyrsvx (fuhcjmitds )
-
31 May 2023
(Breastfeeding with AID*)
Not Applicable
162
(AIRD patients)
doumccqigr(dzosvnvooz) = wdhyjgxylo hbzjmqifxh (dlcsxgdjde )
Positive
31 May 2023
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