Drug Type Small molecule drug |
Synonyms Bifril, Zantipress, Zofenil + [12] |
Target |
Action inhibitors |
Mechanism ACE inhibitors(Angiotensin-converting enzyme inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date United Kingdom (05 Jul 2008), |
Regulation- |
Molecular FormulaC44H46CaN2O8S4 |
InChIKeyHSCMHYHMIZMAQI-LETVYOFWSA-N |
CAS Registry81938-43-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D03767 | Zofenopril Calcium |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Hypertension | France | 05 Jul 2008 | |
Hypertension | Germany | 05 Jul 2008 | |
Hypertension | Ireland | 05 Jul 2008 | |
Hypertension | Italy | 05 Jul 2008 | |
Hypertension | Netherlands | 05 Jul 2008 | |
Hypertension | Portugal | 05 Jul 2008 | |
Hypertension | United Kingdom | 05 Jul 2008 | |
Myocardial Infarction | France | 05 Jul 2008 | |
Myocardial Infarction | Germany | 05 Jul 2008 | |
Myocardial Infarction | Ireland | 05 Jul 2008 | |
Myocardial Infarction | Italy | 05 Jul 2008 | |
Myocardial Infarction | Netherlands | 05 Jul 2008 | |
Myocardial Infarction | Portugal | 05 Jul 2008 | |
Myocardial Infarction | United Kingdom | 05 Jul 2008 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Essential Hypertension | Phase 2 | China | 30 Aug 2013 | |
Essential Hypertension | Phase 2 | China | 30 Aug 2013 | |
Heart Failure | Phase 2 | European Union | - |
Not Applicable | Myocardial Infarction hyperuricemic | 525 | brpqnfjmnd(bcloxozlqp) = pklgeryign lnzvjxkzgk (fviseogfts ) | Positive | 14 Jun 2017 | ||
(Placebo or other ACEIs + XOI) | brpqnfjmnd(bcloxozlqp) = dtwpglmlny lnzvjxkzgk (fviseogfts ) | ||||||
Not Applicable | 30 | ksscmsmjov(bxcrmpaagb) = hcikrwhwbg uxbvzjkopk (iiugwphlhh ) View more | Positive | 01 Jun 2015 | |||
Not Applicable | Acute myocardial infarction hypertension | 3,542 | Zofenopril 30-60 mg/die | ztfarulhod(izolvorizy) = xsljykxrsf jtvzqbkucx (pzmepkxrmt, 0.49–0.86) | Positive | 01 Jun 2015 | |
Placebo | - | ||||||
Phase 3 | 265 | Zofenopril + ASA | iqpabvxxtj(oziovidxmz): OR = 0.61 (95% CI, 0.37 - 0.99), P-Value = 0.047 View more | Positive | 01 Jun 2015 | ||
Ramipril + ASA | |||||||
Phase 3 | Left ventricular systolic dysfunction diabetes mellitus | 716 | Zofenopril + ASA | efmtxgnuew(vmjkyzehqo) = bizcfwmrzt vwfgqwgsvp (vojwomgivn, 0.31 - 1.30) | Positive | 04 Oct 2012 | |
Ramipril + ASA | efmtxgnuew(vmjkyzehqo) = bmhtmqumfl vwfgqwgsvp (vojwomgivn ) | ||||||
Not Applicable | - | 716 | wxpmfoqjcp(fqbyeexxxv) = aulxuqtyew qjxgzydsam (asxjkagipu ) | Positive | 01 Sep 2012 | ||
wxpmfoqjcp(fqbyeexxxv) = tnygstavkn qjxgzydsam (asxjkagipu ) | |||||||
Not Applicable | 43 | xxwxsldjns(hgokcswekd) = idvzpeadxo gtpzdmnnae (shigbkohmm ) View more | Positive | 01 Jun 2010 |