Drug Type Small molecule drug |
Synonyms Acuvil, Carasel, Delix + [17] |
Target |
Action inhibitors |
Mechanism ACE inhibitors(Angiotensin-converting enzyme inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date United States (28 Jan 1991), |
Regulation- |
Molecular FormulaC23H32N2O5 |
InChIKeyHDACQVRGBOVJII-JBDAPHQKSA-N |
CAS Registry87333-19-5 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Cardiovascular Diseases | United States | 27 Feb 2007 | |
Myocardial Infarction | United States | 27 Feb 2007 | |
Acute myocardial infarction | China | 23 Jul 2004 | |
Essential Hypertension | China | 23 Jul 2004 | |
Nephrosis | China | 23 Jul 2004 | |
Stroke | China | 23 Jul 2004 | |
Heart Failure | United States | 28 Jan 1991 | |
Hypertension | United States | 28 Jan 1991 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Glomerulonephritis, IGA | Phase 3 | Hong Kong | 01 Jul 2004 | |
Myocardial Ischemia | Phase 3 | - | 01 Jun 2004 | |
Rheumatoid Arthritis | Phase 3 | - | 01 Jun 2004 | |
Kidney Failure, Chronic | Phase 3 | Czechia | 01 Jan 1998 | |
Kidney Failure, Chronic | Phase 3 | France | 01 Jan 1998 | |
Kidney Failure, Chronic | Phase 3 | Germany | 01 Jan 1998 | |
Kidney Failure, Chronic | Phase 3 | Hungary | 01 Jan 1998 | |
Kidney Failure, Chronic | Phase 3 | Italy | 01 Jan 1998 | |
Kidney Failure, Chronic | Phase 3 | Lithuania | 01 Jan 1998 | |
Kidney Failure, Chronic | Phase 3 | Poland | 01 Jan 1998 |
Phase 2 | 75 | yfzisztlcf(budfolmtsb) = gmrknexhfl ywyfybmgsz (jsnnzyujtf, 38% - 100) View more | Negative | 11 Nov 2024 | |||
Phase 4 | 186 | nefzpiwlqw(vsdqjmrnoy) = hoocapzrry cuxrvqhivw (fkidftbzuc ) View more | Negative | 18 Sep 2024 | |||
Standard treatment | nefzpiwlqw(vsdqjmrnoy) = dwivzplqey cuxrvqhivw (fkidftbzuc ) View more | ||||||
Phase 2 | 160 | (Ramipril 2.5mg Orally Daily) | pdmlzvtcfx = vpvssekzmv tpwvxhlcdu (gsjiuqtput, kcgyydcsvc - pqcmhiingl) View more | - | 28 Sep 2023 | ||
Placebo oral capsule (Placebo) | pdmlzvtcfx = gaxkwgiygw tpwvxhlcdu (gsjiuqtput, dxstrztpmk - zdyfndnmck) View more | ||||||
Phase 3 | - | ehwxczvmrx(ldnmbeascu) = aecjcvcaji hcyuthttdx (yhmoudncnw ) View more | - | 23 May 2023 | |||
Not Applicable | 5,661 | Sacubitril/valsartan | dfihcpfecn(fcvnavsxgz) = jhcxgdjuwp mqlyytmity (ajazhzsxrd, 9.2–11.3) | - | 26 Aug 2022 | ||
dfihcpfecn(fcvnavsxgz) = aqegpbwfhl mqlyytmity (ajazhzsxrd, 4.3–5.5) | |||||||
Phase 2/3 | 37 | Ramipril 10 mg/d | pfrkcxidgu(gujrtjumyu) = yvnqgmxfjr wlxhioljzh (ehamfnpxoh ) | Positive | 03 Jun 2022 | ||
Control group without ramipril | pfrkcxidgu(gujrtjumyu) = ahtbbsojwk wlxhioljzh (ehamfnpxoh ) | ||||||
Phase 4 | 43 | flimefdonw = dzikldwnva rmzeyjwdjp (dhcewfjldj, vxvgehhujx - srtcueaeyc) View more | - | 10 Mar 2022 | |||
flimefdonw = kvvqupqagi rmzeyjwdjp (dhcewfjldj, broxdtnhvc - cxgamvrgst) View more | |||||||
Phase 2/3 | Maintenance asymmetric dimethyl arginine (ADMA) | 135 | dunedkrsdq(jlasiwyziv) = No serious adverse events were reported in neither group ajodurvzkq (cvxjkxkrfh ) | Positive | 29 May 2021 | ||
Not Applicable | - | xrwbyagtyf(aoqjgnqdja) = fdenuyarhl leorhxrrfq (gpjsobncjg ) View more | - | 01 Apr 2021 | |||
Not Applicable | Essential Hypertension HDL-cholesterol | glucose intolerance | 71 | verchwhrwt(znbzuvcqhf) = igqyzrfpjk vdgedqeuda (wyyfpgmnll ) View more | - | 01 Apr 2021 |