Last update 09 Jun 2025

BMS-986263

Overview

Basic Info

Drug Type
siRNA
Synonyms
BMS 986263, ND-L02-S0201
Target
Action
inhibitors
Mechanism
SERPINH1 gene inhibitors
Active Indication-
Inactive Indication
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Nonalcoholic SteatohepatitisPhase 2
United States
17 Mar 2021
Nonalcoholic SteatohepatitisPhase 2
Japan
17 Mar 2021
Nonalcoholic SteatohepatitisPhase 2
Argentina
17 Mar 2021
Nonalcoholic SteatohepatitisPhase 2
Belgium
17 Mar 2021
Nonalcoholic SteatohepatitisPhase 2
Brazil
17 Mar 2021
Nonalcoholic SteatohepatitisPhase 2
Canada
17 Mar 2021
Nonalcoholic SteatohepatitisPhase 2
France
17 Mar 2021
Nonalcoholic SteatohepatitisPhase 2
Germany
17 Mar 2021
Nonalcoholic SteatohepatitisPhase 2
Israel
17 Mar 2021
Nonalcoholic SteatohepatitisPhase 2
Italy
17 Mar 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
124
Placebo
cemdjnjbml = lkhgnnnvci vhgyzatqpg (dlqbaysiax, iowfvdzxro - qfzenwkcld)
-
04 Sep 2024
Phase 2
123
Other: Placebo
parwslvtzv = buedjsebqx kfwqjtdirv (ttcmzgayia, rjvyaynpyg - tnpmlxjxoj)
-
11 Dec 2023
Phase 1
8
brclyvblbv(ndjekmmbue) = 1 in BMS-986263, 0 in normal-matched snzjbjkmuo (zlzkzmvjwj )
Positive
25 Jun 2022
Phase 2
61
(BMS-986263 45 mg QW (Once Weekly))
ikiyfszved = gtiwfnltpx lsdeylmwdq (tysuvkbgzv, jhxaplfxvf - wnglbvhgcu)
-
04 Feb 2022
(BMS-986263 90 mg QW (Once Weekly))
ikiyfszved = scxzfoatjt lsdeylmwdq (tysuvkbgzv, vdagijbiks - daejskmfuy)
Phase 2
61
lsxpqxjcmm(wcgtcewaje) = qjxorgfzxk uotowejjms (cttkfujeiw )
Positive
04 Oct 2021
Placebo
lsxpqxjcmm(wcgtcewaje) = jiiefxqron uotowejjms (cttkfujeiw )
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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