Last update 03 Oct 2024

Artesunate/Chlorproguanil/Dapsone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CDA, Chlorproguanil/dapsone/artesunate, Dacart
Mechanism
ATP2A1 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 inhibitors), DHPS inhibitors(Dihydropteroate synthase inhibitors), SERCA2 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 inhibitors)
Therapeutic Areas
Active Indication-
Inactive Indication
Originator Organization-
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-

Structure

Molecular FormulaC12H12N2O2S
InChIKeyMQJKPEGWNLWLTK-UHFFFAOYSA-N
CAS Registry80-08-0
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Malaria, FalciparumPhase 3
BF
01 Apr 2006
Malaria, FalciparumPhase 3
GH
01 Apr 2006
Malaria, FalciparumPhase 3
ML
01 Apr 2006
Malaria, FalciparumPhase 3
NG
01 Apr 2006
MalariaPhase 3---
MalariaPhase 3--
MalariaPhase 3--
MalariaPhase 3--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
1,372
djtsmarnfs(wtickslvzd) = ilyjmlghun cmchgrxjkg (rlqmnpcboh )
Negative
19 Aug 2009
djtsmarnfs(wtickslvzd) = vmuhqlxini cmchgrxjkg (rlqmnpcboh )
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Approval

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Regulation

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