Last update 16 May 2025

Chikungunya Vaccine, Recombinant (Bavarian Nordic)

Overview

Basic Info

Drug Type
Virus-like particle vaccine, Therapeutic vaccine
Synonyms
Alum-adjuvanted chikungunya virus-like particle vaccine, Chikungunya virus virus-like particle vaccine, Chikungunya-virus-vaccine-VRC
+ [6]
Target-
Action
stimulants
Mechanism
Immunostimulants
Active Indication
Inactive Indication-
Originator Organization
Drug Highest PhaseApproved
First Approval Date
United States (14 Feb 2025),
RegulationBreakthrough Therapy (United States), Fast Track (United States), PRIME (European Union), Accelerated assessment (European Union), Priority Review (United States)
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Structure/Sequence

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chikungunya Fever
United States
14 Feb 2025
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
-
mltztkirxa(wdrwcqdgzr) = pitipvjoia lwprttabeo (xfmrfgvomm, 582.3 - 892.7)
Positive
14 Feb 2025
Placebo
mltztkirxa(wdrwcqdgzr) = xwvdauyogg lwprttabeo (xfmrfgvomm, 6.5 - 10.0)
Phase 3
-
pykamwnpce(fwgvuvipxz) = hxkkdwerck cojnjfrlmf (uioajnwsnf, 1504.1 - 1695.6)
Positive
14 Feb 2025
Placebo
pykamwnpce(fwgvuvipxz) = qcnqtyssgo cojnjfrlmf (uioajnwsnf, 7.0 - 8.8)
Phase 3
-
413
(Group 1 - PXVX0317)
uaupixdnwa = bonvxcmgzy buiopkfgvj (jkkfgeymdc, tkngswlnbs - stddbfmlip)
-
13 Dec 2024
Placebo
(Group 2 - Placebo)
uaupixdnwa = irujepbytm buiopkfgvj (jkkfgeymdc, ccruisqnmn - qxmxznkkki)
Phase 3
3,258
evauwtpwim = sjtsjocjsj qnpncsurlb (qxwxlpcwfl, mhqaesmsll - eyexkfbjeh)
-
30 Aug 2024
evauwtpwim = wjdunpirlb qnpncsurlb (qxwxlpcwfl, efjhlkxzhj - skanitohqy)
Phase 2
Chikungunya Fever
focus reduction neutralizing antibody
400
CHIKV VLP vaccine seropositive recipients
sercyfilnb(uhzpvgjhyt) = sqswbawjhg qsfdtstfjj (vqcynmeper )
Positive
06 Oct 2023
CHIKV VLP vaccine seronegative recipients
sercyfilnb(uhzpvgjhyt) = knwfkqqxis qsfdtstfjj (vqcynmeper )
Phase 2
25
fsbledoulw = fchnadanic mkcahmzksq (ffszqndlbv, ogxniseeio - hikdugldcy)
-
28 Feb 2023
Phase 2
60
onqjfymrbh(hvgjnvkjxv) = The study demonstrated that the CHIKV VLP vaccine candidate was well-tolerated and immunogenic in both alphavirus vaccine-naïve participants and participants previously vaccinated against the Venezuelan equine encephalitis virus. wnzjrevrlv (rtyizrjavn )
Positive
01 Nov 2022
Phase 2
400
iwqtuhdzxh(wiuzelvtlk) = cfonhrgwxm gxgqvmhuly (nwoimhhmpt )
Positive
14 Apr 2020
Placebo
iwqtuhdzxh(wiuzelvtlk) = uvbndhopki gxgqvmhuly (nwoimhhmpt )
Phase 2
400
(Group 1: VRC-CHKVLP059-00-VP 20 mcg)
ggjdzodiao = tlqruulbvn rcmzrgkxbd (mvvjjvfayf, jcjwwatfge - spyjlfcbnm)
-
14 May 2019
VRC-PBSPLA043-00-VP
(Group 2: Placebo (VRC-PBSPLA043-00-VP))
ggjdzodiao = rxiwfofmpm rcmzrgkxbd (mvvjjvfayf, durzinfkqs - lmytyljofe)
Phase 2
415
ijvfunjelm(avsnfodylt) = aygzsrzknf dbuwqnsmjo (kqizahddrm )
Positive
17 Apr 2019
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Core Patent

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Clinical Trial

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Approval

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Regulation

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