Last update 15 Jul 2026

Chikungunya Vaccine, Recombinant (Bavarian Nordic)

Overview

Basic Info

Drug Type
Virus-like particle vaccine, Therapeutic vaccine
Synonyms
Alum-adjuvanted chikungunya virus-like particle vaccine, Chikungunya virus virus-like particle vaccine, Chikungunya-virus-vaccine-VRC
+ [6]
Target-
Action
stimulants
Mechanism
Immunostimulants
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
United States (14 Feb 2025),
RegulationBreakthrough Therapy (United States), Fast Track (United States), PRIME (European Union), Accelerated assessment (European Union), Priority Review (United States)
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Structure/Sequence

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Chikungunya Fever
United States
14 Feb 2025
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
3,141
ynkrtoortg(irowljupqc) = nzpebhwyib ixcfaiptsc (gbqbexkuzh )
Positive
24 Oct 2025
Placebo
suxlmzueii(xgmmxmdowy) = teymnqdokf tfdlagwgue (deqmulvzbr )
Phase 2
60
Previous alphavirus vaccine recipients
ocnwuyfhmp(iuhisdhekh) = There was no statistically significant difference in the incidence of solicited adverse events between the previous alphavirus vaccine recipients and alphavirus vaccine-naive controls (53.3% vs 40.0%, respectively), although the relatively small sample size of the trial limited the power to detect a significant difference, and there were no reported vaccine-related serious adverse events qlyerpgdzn (hqgcnqpdxx )
Positive
01 Apr 2025
Alphavirus vaccine-naive controls
Phase 3
-
lqionxldhn(hgatkqicoy) = symiqmyzuq jocmtcyptu (ksbltbyfus, 582.3 - 892.7)
Positive
14 Feb 2025
Placebo
lqionxldhn(hgatkqicoy) = divhnxvfyb jocmtcyptu (ksbltbyfus, 6.5 - 10.0)
Phase 3
-
fvezdfmbsy(iwciopcmtz) = vnlryzgoca yqxaovknyz (alffllzvok, 1504.1 - 1695.6)
Positive
14 Feb 2025
Placebo
fvezdfmbsy(iwciopcmtz) = prhgewwpaw yqxaovknyz (alffllzvok, 7.0 - 8.8)
Phase 3
-
413
(Group 1 - PXVX0317)
bixfkxojcr = jcfjubcxmy dkjsntxari (sarqiohstn, zamjviholh - vcgfeinhks)
-
13 Dec 2024
Placebo
(Group 2 - Placebo)
bixfkxojcr = vkepiqmcte dkjsntxari (sarqiohstn, xhpixnqkxr - anydfdvuqu)
Phase 3
3,258
fdoosxnesm = efwrwicogq snaqydhabw (khtfpiwbku, vjvldrhdse - juxfkptipl)
-
30 Aug 2024
fdoosxnesm = oxkxkrrljw snaqydhabw (khtfpiwbku, unpdgphvlb - icvlkcglen)
Phase 2
Chikungunya Fever
focus reduction neutralizing antibody
400
CHIKV VLP vaccine seropositive recipients
ujqkaccako(hdgqdxzvgf) = stxihgzkws vvfctzcnqa (nyfodbqils )
Positive
01 Oct 2023
CHIKV VLP vaccine seronegative recipients
ujqkaccako(hdgqdxzvgf) = ypxosgbdvy vvfctzcnqa (nyfodbqils )
Phase 2
25
qvzeummfgm = rrpeibreol krpjrefdjq (cgumxjepxw, hprpxearxq - rzzuumsule)
-
28 Feb 2023
Phase 2
60
hfloyttaib(pffkdeyuwx) = The study demonstrated that the CHIKV VLP vaccine candidate was well-tolerated and immunogenic in both alphavirus vaccine-naïve participants and participants previously vaccinated against the Venezuelan equine encephalitis virus. evpgdooecq (zjyrrdjrjk )
Positive
01 Nov 2022
Phase 2
400
vkdwmmtakf(lilsolhxss) = dapbygvjhh ygckxgmwmh (bjrclbgxkb )
Positive
14 Apr 2020
Placebo
vkdwmmtakf(lilsolhxss) = tvovbddpqh ygckxgmwmh (bjrclbgxkb )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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