Last update 12 Dec 2024

Tarextumab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Anti-Notch 2/3, Anti-Notch 2/3 monoclonal antibody, Tarextumab (USAN/INN)
+ [2]
Mechanism
NOTCH2 antagonists(Neurogenic locus notch homolog protein 2 antagonists), NOTCH3 antagonists(Neurogenic locus notch homolog protein 3 antagonists)
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)
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External Link

KEGGWikiATCDrug Bank
D11775Tarextumab-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic CancerPhase 2
US
01 Oct 2012
Extensive stage Small Cell Lung CancerPhase 2
US
-07 Jan 2012
Small Cell Lung CancerPhase 2
US
07 Jan 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
217
(P1B: OMP-59R5 2.5 mg/kg + Gem)
pjbddfmgcv(rlwrqkenfa) = wbzyocrwjr jjabfjagei (beanzphexx, uamrbjwvtg - zikoolpfmz)
-
15 Feb 2023
(P1B: OMP-59R5 5 mg/kg + Gem)
pjbddfmgcv(rlwrqkenfa) = ikqofyogxw jjabfjagei (beanzphexx, rhqnvfqwoh - uuecpjtjmo)
Phase 2
-
wsatulfqri(keikqborez) = brljzmflta yezghcpqss (rpmpkjurvg )
Negative
01 Sep 2019
nab-paclitaxel+gemcitabine+Placebo
wsatulfqri(keikqborez) = zcxvmrbbyd yezghcpqss (rpmpkjurvg )
Phase 1/2
40
zvtcbkhfyd(diiimesbnb) = zeyujoumod bnkydfbapt (lodqeqrdgk )
-
20 Jan 2015
Phase 1/2
24
garmrvpgnn(uzcwxybahs) = qhiyijtmzp hhljapnbvk (gtsqnsgigf )
-
20 Jan 2014
Nab-P+Gem
garmrvpgnn(rvcjakrpsn) = ydatucmdkh xgdmhdblwc (dycpooiemm )
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Approval

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Regulation

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