Drug Type Bispecific antibody |
Synonyms anti-PD-L1 monoclonal antibody-VEGFR1 fusion protein, HB 0025, HB-0025 + [1] |
Target |
Mechanism PDL1 inhibitors(Programmed death-ligand 1 inhibitors), VEGF inhibitors(Vascular endothelial growth factor inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Advanced Endometrial Carcinoma | Phase 2 | CN | 06 Sep 2023 | |
Advanced Malignant Solid Neoplasm | Phase 2 | CN | 18 Jul 2023 | |
Kidney Neoplasms | Phase 2 | CN | 21 Feb 2023 | |
Hepatocellular Carcinoma | IND Approval | CN | 10 Nov 2023 | |
Neoplasms | Preclinical | CN | 02 Dec 2021 | |
Neoplasms | Preclinical | CN | 02 Dec 2021 |
NCT06222125 (ASCO2024) Manual | Phase 1/2 | 17 | HB0025 10mg/kg | mldeqlgvvt(rwnjijtchx) = cqswqaekik kqjnmwhgoo (lsunmpnaih, 1.7 - 40.5) View more | Positive | 24 May 2024 | |
Phase 1 | Non-Small Cell Lung Cancer EGFR/ALK mutation | EGFR/ALK wild-type gene | 12 | byknbzaasq(lnmsidpnye) = 33.3%, 4/12 mwrbmffyhn (agygikksza ) View more | Positive | 24 May 2024 | ||
NCT04678908 (ASCO2023) Manual | Phase 1 | 30 | ailcexebey(ffqhredqgf) = gyoawwmvpk jlnkdjntzv (cwyrxuzqor ) View more | Positive | 26 May 2023 |