Last update 12 Dec 2024

Zamzetoclax

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
MCL1 inhibitor - Gilead Sciences, GS 9716, GS-9716
Target
Mcl-1
Mechanism
Mcl-1 inhibitors(Induced myeloid leukemia cell differentiation protein Mcl-1 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Gilead Sciences, Inc.Gilead Sciences, Inc.
Active Organization
Gilead Sciences, Inc.Gilead Sciences, Inc.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure

Molecular FormulaC38H46ClN5O6S
InChIKeyGRGIAFGOQJYTKU-ZRZJLSGHSA-N
CAS Registry2388470-64-0

Related

1
Clinical Trials associated with Zamzetoclax
NCT05006794 / RecruitingPhase 1
A Phase 1a/b Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GS-9716 as Monotherapy and in Combination With Anticancer Therapies in Subjects With Solid Malignancies
100 Clinical Results associated with Zamzetoclax
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100 Translational Medicine associated with Zamzetoclax
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100 Patents (Medical) associated with Zamzetoclax
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100 Deals associated with Zamzetoclax
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
US
Gilead Sciences, Inc.Gilead Sciences, Inc.
15 Sep 2021
Advanced Malignant Solid NeoplasmPhase 1
IL
Gilead Sciences, Inc.Gilead Sciences, Inc.
15 Sep 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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