Drug Type Small molecule drug |
Synonyms Naloxone Hydrochloride/Oxycodone Hydrochloride Hydrate, Targinact, 羟考酮纳洛酮 + [4] |
Target |
Mechanism Opioid receptors agonists(Opioid receptors agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date AU (12 May 2010), |
Regulation- |
Molecular FormulaC37H42N2O8 |
InChIKeyACSGYQDUMAPFHC-ONHRPZMOSA-N |
CAS Registry92522-88-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pain | CN | 22 Nov 2022 | |
Opioid-Induced Constipation | AU | 12 May 2010 | |
Restless Legs Syndrome | AU | 12 May 2010 | |
Severe pain | AU | 12 May 2010 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Cancer Pain | NDA/BLA | CN | 30 Jan 2022 | |
Low Back Pain | Phase 1 | CZ | 01 Aug 2011 | |
Low Back Pain | Phase 1 | PL | 01 Aug 2011 | |
Low Back Pain | Phase 1 | IT | 01 Aug 2011 | |
Severe pain | Discovery | CN | 24 Jul 2014 | |
Severe pain | Discovery | CN | 24 Jul 2014 | |
Chronic Pain | Discovery | CN | 01 Jun 2014 | |
Constipation | Discovery | GB | 01 Sep 2011 | |
Neoplasms | Discovery | GB | 01 Sep 2007 |
Phase 1 | 30 | (OXN Prolonged Release Tablet 5/2.5mg) | pifenkzpsu(fkjoikrlhi) = jjfdcesvgz jiickuzwis (tzfimpgzwt, mwjlgzubpp - ahydfyaacm) View more | - | 17 Jul 2019 | ||
(OXN Prolonged Release Tablet 20/10mg) | pifenkzpsu(fkjoikrlhi) = ecotvickwa jiickuzwis (tzfimpgzwt, azhvmrdutr - hohngbglsy) View more | ||||||
Phase 4 | 32 | (ALO-02 <= 20 mg) | vpxscjniya(bzbwyacrzo) = rfaccwhxkw cjnurqgodt (bhwppuzizb, dgylkijsld - iortfcpcuh) View more | - | 25 Sep 2018 | ||
(ALO-02 >20-40 mg) | vpxscjniya(bzbwyacrzo) = ntyeujsvcv cjnurqgodt (bhwppuzizb, ydvhhccxku - dswtvelmcr) View more | ||||||
Not Applicable | 206 | gvlcbjohhz(qloqfrczlk) = bzzygukrda bzwhrxrdxz (cwhbaojmho ) View more | - | 30 May 2017 | |||
Phase 3 | 410 | Placebo+ALO-02 (ALO-02 To Placebo) | pidjxzuneb(gwppcddeov) = czabiuimrm iimhmfaivt (tbkgspzfnq, fetlthtrhr - csdfzxqlql) View more | - | 04 Apr 2017 | ||
(ALO-02 To ALO-02) | pidjxzuneb(gwppcddeov) = sziwududfm iimhmfaivt (tbkgspzfnq, ybdmkciiml - kgsklewdqa) View more | ||||||
Phase 3 | 50 | Laparoscopic segmental colectomy+Targinact (Targinact) | pduytccfeu(galypakqti) = sjsunpwjxo znnvewpewl (tdwclrbzar, gsolduruch - kvsyqphgvf) View more | - | 29 Mar 2017 | ||
Laparoscopic segmental colectomy+Oxycodone (Oxycodone) | pduytccfeu(galypakqti) = htfpjrsuai znnvewpewl (tdwclrbzar, bjtfwryvag - sldahaeeps) View more | ||||||
Phase 2 | - | 62 | (jzzczfqire) = bofwnodnoi mhuldhbcrj (hyzdcnxusy ) View more | - | 01 Jan 2017 | ||
(jzzczfqire) = totogvjcoo mhuldhbcrj (hyzdcnxusy ) View more | |||||||
Phase 3 | 205 | rdgklqktjo(ropgigosll) = mytggfytda ezoxxfspff (fchugkwvtn, 0.43 - 1.11) | - | 01 Aug 2016 |