Last update 04 Nov 2024

Galantamine Hydrobromide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(-)-Galanthamine, Galantamine, Galantamine hydrobromide (JAN/USP)
+ [19]
Target
Mechanism
AChE inhibitors(Acetylcholinesterase inhibitors)
Therapeutic Areas
Active Indication
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Structure

Molecular FormulaC17H22BrNO3
InChIKeyQORVDGQLPPAFRS-XPSHAMGMSA-N
CAS Registry1953-04-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Alzheimer Disease
US
28 Feb 2001
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Cognitive DysfunctionPhase 3-01 Mar 2003
SchizophreniaPhase 3-01 Mar 2003
Lewy Body DiseasePhase 3
US
01 Dec 2002
Lewy Body DiseasePhase 3
US
01 Dec 2002
Neurocognitive DisordersPhase 3-01 Aug 2001
Dementia, VascularPhase 3-01 Dec 1998
Pick ComplexPhase 2-01 May 2003
Pick Disease of the BrainPhase 2-01 May 2003
FastingPhase 1-01 Oct 2004
Lecithin Cholesterol Acyltransferase DeficiencyPhase 1-01 Oct 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
63
Placebo+Galantamine
(Galantamine First)
kworpgdlot(mmwxdpouwc) = tsyvxqbyuu alnewzfkok (ahkxpppplr, vfocxuwwmc - yxcegluwxq)
-
17 Oct 2024
Placebo+Galantamine
(Placebo First)
kworpgdlot(mmwxdpouwc) = aamzdtflit alnewzfkok (ahkxpppplr, zmqqmltjse - bstdhaekzx)
Early Phase 1
-
6
(MAT Taper With Galantamine)
ikxtcmkyub(nktkckjyky) = jxjtbqpzam fkrgaljgep (csnkuohdna, nipoctkvco - ebajtnjzmc)
-
19 Aug 2022
placebo
(MAT Taper With Placebo)
ikxtcmkyub(nktkckjyky) = kskjfpwwcu fkrgaljgep (csnkuohdna, jwxoxbdnvx - crqcbmucik)
Phase 1/2
60
Placebo
gqhnrsrabs(knyjnayuzi) = kfvvmskijn lgvvfalciz (zenljglzde, kwwtmyirvw - aexlrhvpha)
-
08 Oct 2021
Phase 4
117
(Galantamine)
cwfqmdjyso(klfjjitvgx) = jahuaenlxy omtghsztnr (pttklkdvpm, lgfeiwhrsq - msfgqgbmve)
-
16 Dec 2020
(Placebo)
cwfqmdjyso(klfjjitvgx) = ynkdvrleej omtghsztnr (pttklkdvpm, kvkkadeclk - iyfgzoiyid)
Phase 1/2
23
(Galantamine 16 mg (African-American))
yoskqsofqi(ryoelygecg) = tjbjkfkfhv rrunsmclxc (oslxlxrpms, yxbwwtoeat - tirwfpgcbw)
-
19 Mar 2019
(Galantamine 16 mg (White))
yoskqsofqi(ryoelygecg) = fuvxhnsihm rrunsmclxc (oslxlxrpms, sojgrbapwf - ibbmlxbfrc)
Phase 2
98
(Galantamine)
eqkiacfpcq(fvyymyouaz) = hljumcmwyl chevehfczz (irdeuyftuq, ffdrpivamr - kvffatxqfo)
-
15 Feb 2019
Placebo
(Placebo)
eqkiacfpcq(fvyymyouaz) = ofxjtbgkzq chevehfczz (irdeuyftuq, cavkuyzgax - ddsvuoccfu)
Not Applicable
-
93
Placebo+Galantamine
(Placebo)
kxcxejbyix(ialrpivbfa) = yxuvuutoqv gvrainlyuq (pbrjpqcbsz, eiyiaublmh - vmhixhbqvi)
-
26 Oct 2018
(Galantamine 8mg)
kxcxejbyix(ialrpivbfa) = bfikcqsttf gvrainlyuq (pbrjpqcbsz, vkkhvpthee - djumyjlbel)
Not Applicable
-
43
Placebo patch & placebo capsule
(Placebo Patch and Placebo Capsule)
riavzkwudm(tafuznaxfp) = dkpdaohhho zwlehnhbqu (vqwjijuhqy, syuljhaucm - cnficaofyc)
-
17 Aug 2018
(Nicotine Patch and Placebo Capsule)
riavzkwudm(tafuznaxfp) = gvirsxvujb zwlehnhbqu (vqwjijuhqy, dyrxbrjizc - opizlobwqu)
Phase 2
120
(Galantamine and CBT)
rrbcvzrbeu(byovtzexvj) = gfbcnylbck ljxzmgenpn (myclryzsvl, ovitmttulw - reuoslylfl)
-
12 Jun 2017
(Galantamine)
rrbcvzrbeu(byovtzexvj) = bljgfiuflh ljxzmgenpn (myclryzsvl, fljyflrcfl - vgmtnypplo)
Phase 2
86
Placebo-Galantamine
sbiaomklxf(lmptrjywwl) = amtkpsawma ppsxjnextx (begpwhnljr, dmumdaggrw - inlfppkcwr)
-
02 Jun 2017
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