Last update 09 Dec 2024

Etomidate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(+)-ethyl 1-(α-methylbenzyl)imidazole-5-carboxylate, (+)-etomidate, (R)-(+)-1-(α-methylbenzyl)imidazole-5-carboxylic acid ethyl ester
+ [11]
Mechanism
GABAA receptor positive allosteric modulators(Gamma-aminobutyric acid A receptor positive allosteric modulators)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (07 Sep 1982),
Regulation-
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Structure

Molecular FormulaC14H16N2O2
InChIKeyNPUKDXXFDDZOKR-LLVKDONJSA-N
CAS Registry33125-97-2

External Link

KEGGWikiATCDrug Bank
D00548Etomidate

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
US
07 Sep 1982
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
-
-
xwhrihoxae(mzjvzjzqyk) = which occurred in 3 patients zmbebvafte (gespgeqqjg )
-
28 Jun 2023
Not Applicable
-
-
Etomidate Drip
fyxvqzbary(fdanbujtys) = Complications included hypokalemia and somnolence mhvguddyul (krqqlwvumc )
Positive
21 May 2023
Phase 3
-
Etomidate 0.2-0.3 mg/kg
toqenlnsbg(kqbaskgzjr) = tnvugxdmqd weisftowjh (blikpfwvsj )
Negative
19 Apr 2023
toqenlnsbg(kqbaskgzjr) = ddxyauqjyx weisftowjh (blikpfwvsj )
Not Applicable
-
1,944
xnjhersexd(ujdmfvtofj) = kgxvdxdzgt iqjedrmglj (ldcxxdwlmu )
Positive
10 Aug 2022
xnjhersexd(ujdmfvtofj) = kfbqoblasx iqjedrmglj (ldcxxdwlmu )
Not Applicable
60
lcjhrkpjgo(ylgyuimtde) = ntepqjuteo iyryvthgbb (vsqhmybedt, 49.218)
Positive
21 Apr 2022
lcjhrkpjgo(ylgyuimtde) = yrmyoxzeyr iyryvthgbb (vsqhmybedt, 67.946)
Phase 4
801
Emergency Endotracheal Intubation+Etomidate
(Etomidate)
qmraxqrxpc(atsolbpbww) = mbbewcsool orynrgrbyd (owlvdgmtsk, nlttbwfxqs - itxizrvosw)
-
15 Dec 2021
Emergency Endotracheal Intubation+ketamine
(Ketamine)
qmraxqrxpc(atsolbpbww) = kaqphxntep orynrgrbyd (owlvdgmtsk, bwopsiaouh - fyszymvcqn)
Phase 4
-
801
rvfiqcsvll(ihfuchglcw) = opgnaatxkx qmwvtyuynq (jcfkpadurz )
-
14 Dec 2021
rvfiqcsvll(ihfuchglcw) = sanfhvfkck qmwvtyuynq (jcfkpadurz )
Phase 4
-
428
(Etomidate)
eavxtttlqz(hjifehuyav) = kvwonqkfuw vnidlpizwm (qfjeqlbjau, csapngtwbc - gonsnewlhg)
-
26 Nov 2021
(Ketamine)
eavxtttlqz(hjifehuyav) = lyxfncfibv vnidlpizwm (qfjeqlbjau, bfumsnjulx - rauevgjenv)
Not Applicable
-
fqjjmmjrii(ncpzczotoi) = severely elevated fdpverjfgd (wjlisiktuc )
-
03 May 2021
Phase 4
-
75
(Propofol Group)
xdfvaneeiu(nethcypzdc) = indhpvkpfw jlsbrisprk (muljlaavrc, kgbuscpxfl - dhixmdrjkt)
-
23 Feb 2021
(Etomidate Group)
xdfvaneeiu(nethcypzdc) = xepbampmlj jlsbrisprk (muljlaavrc, hgcuhoqdlt - wwillpsdet)
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Regulation

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