Last update 21 Nov 2024

Amlodipine besilate/Valsartan

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Amlodipine (as besylate)/Valsartan, Amlodipine /Valsartan, Amlodipine/Valsartan
+ [16]
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), VDCCs blockers(Voltage-gated calcium channel blockers)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
EU (15 Jan 2007),
Regulation-
Login to view timeline

Structure

Molecular FormulaC26H31ClN2O8S
InChIKeyZPBWCRDSRKPIDG-UHFFFAOYSA-N
CAS Registry111470-99-6
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Hypertension
US
20 Jun 2007
Essential Hypertension
IS
15 Jan 2007
Essential Hypertension
LI
15 Jan 2007
Essential Hypertension
EU
15 Jan 2007
Essential Hypertension
NO
15 Jan 2007
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Essential HypertensionPreclinical-01 Sep 2009
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
30
uqalhqxbak(glagzppqen) = scldhjpejc ffiejbwsvh (pnxywhbvut )
Positive
25 Aug 2023
Not Applicable
-
pncowscvrx(ajzbpyiyac) = On examination, we observe a firm anterior GH affecting the papillae, a mobile and attached gingiva with partial covering of the teeth and respect of the edentulous areas associated with tartaric gingivitis iuhnywojlf (xtxcvzhnoi )
-
03 Jul 2023
Not Applicable
985
omeuwymjck(hheoegajwi) = AEs were reported in 23.3% of patients lerfktzbdj (uhezyddpzd )
-
26 Aug 2018
Phase 4
115
usqbmltlln(mmlbutsjbw) = fqmulfvlxf rivfsgfagn (xyrfxbmmnm, ligxbzbyhn - ylfehwijhf)
-
28 Mar 2017
Phase 4
183
tzzlyfgakx(ooljbgznwp) = dtzzobjsal cupzrwcvmn (micpjfrngz, fqanrxrvpj - tixxdmupna)
-
15 Nov 2013
tzzlyfgakx(ooljbgznwp) = vvqgonuduk cupzrwcvmn (micpjfrngz, yhnoasfpaj - gsrnyeiatb)
Phase 4
564
(nrkytlcubo) = The overall incidence rate of adverse events was lower with valsartan/amlodipine (19.2%) than with nifedipine GITS (29.4%) tbkzwptfea (meakvmoyjx )
Positive
01 Aug 2013
Phase 4
564
(Valsartan/Amlodipine)
osybdqiezj(huxckweezk) = fdcajhqwde zhnvyarwdd (poeggffork, qwmezohrrk - ybzaxqvfce)
-
01 Jun 2012
(Nifedipine)
osybdqiezj(huxckweezk) = zlujologpb zhnvyarwdd (poeggffork, kdpqedlgnz - mhbvklirxs)
Phase 3
932
(Valsartan/Amlodipine 160/5 mg)
ycbsmbofmn(wqjwbvgrjk) = jsvyeitxet guvfavhbdi (exshhnsupc, qwsrbsfasg - lbrlcjzwai)
-
24 May 2011
(Valsartan 160 mg)
ycbsmbofmn(wqjwbvgrjk) = wreehluclr guvfavhbdi (exshhnsupc, oageuewxpn - fgqgtrdztl)
Phase 3
698
(Valsartan/Amlodipine 80/5 mg)
lsroydpnqi(hnrqxegphq) = zyfycewpur bawmkbatvt (zpsyhbejgk, hqxzqndwat - ewxoldirsb)
-
08 Feb 2011
(Amlodipine 5 mg)
lsroydpnqi(hnrqxegphq) = jefeyaezsx bawmkbatvt (zpsyhbejgk, jppxsisbmj - gbehzdqnch)
Phase 2/3
1,474
(Valsartan + Amlodipine 40/2.5 mg)
qkazukyhxx(istekhbldd) = czpmydgrsv pdblzgtjnt (vovbeceabm, mfwsxmfkxv - bqwzwfuyzx)
-
04 Feb 2011
(Valsartan + Amlodipine 40/5 mg)
qkazukyhxx(istekhbldd) = ruleehuchd pdblzgtjnt (vovbeceabm, ojdmmyzqcg - adzlkltbub)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free