Drug Type Small molecule drug |
Synonyms HBW 3220, HBW-3-20, HBW-3220 + [1] |
Target |
Mechanism BTK C481S inhibitors(Bruton Tyrosine Kinase C481S inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
B-Cell Lymphoma | Phase 2 | CN | 09 May 2022 | |
Autoimmune Diseases | Phase 1 | CN | - | |
Glomerulonephritis | IND Approval | CN | 30 Jun 2023 |
AACR2024 Manual | Phase 1 | 28 | ojcfrixhfa(iftqjmldyh) = Adverse events (AEs), similar to other BTKis, were mostly Grade 1 or 2, including fever (38%), diarrhea (35%), headache (19%), anemia (42%), infectious pneumonia (23%), decreased neutrophils (42%), decreased platelet count (27%), increased alanine aminotransferase (23%), etc. plqbiqlrvg (sbuwzkampy ) View more | Positive | 05 Apr 2024 | ||
CTR20221130 (ASCO2023) Manual | Phase 1 | 11 | qvenynygnm(aqoazvbivg) = hoqckyadze auyewypmen (mptdjdxfbx ) View more | Positive | 31 May 2023 | ||
Not Applicable | - | - | fpvlymxhzu(nivxebaizv) = ujmrkggpgo jhflvwjeux (uslfvxoylz ) View more | - | 09 Jun 2021 | ||
fpvlymxhzu(nivxebaizv) = wglgeifrqt jhflvwjeux (uslfvxoylz ) View more |