Last update 20 Mar 2025

Doripenem

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DRPM, Doripenem Hydrate, Doripenem hydrate (JP17)
+ [9]
Target
Action
inhibitors
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors)
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
RegulationOrphan Drug (United States)
Login to view timeline

Structure/Sequence

Molecular FormulaC15H24N4O6S2
InChIKeyAVAACINZEOAHHE-VFZPANTDSA-N
CAS Registry148016-81-3
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
D01836Doripenem

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Meningococcal Infections
Japan
17 Mar 2015
Paediatric infections
Japan
10 Apr 2013
Gram-Negative Bacterial Infections
Japan
08 Sep 2005
Gram-Positive Bacterial Infections
Japan
03 Sep 2005
Urinary Tract Infections
Japan
30 Aug 2005
Bacterial Infections
Japan
25 Jul 2005
Respiratory Tract Infections
Japan
25 Jul 2005
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Hospital-acquired pneumoniaPhase 1
Liechtenstein
25 Jul 2008
Hospital-acquired pneumoniaPhase 1
European Union
25 Jul 2008
Complicated urinary tract infectionPhase 1
United States
12 Oct 2007
PyelonephritisPhase 1
United States
12 Oct 2007
Complicated urinary tract infectionDiscovery
United States
12 Oct 2007
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
598
mrnikynvab(edcanaurba) = turaingjje vfsmqlpcbu (cjnvpvrzfh, qdpzvqstam - knzcycwsxz)
-
09 Mar 2016
Phase 3
641
hyriwgiaxc(mhlfkpwtmw) = xllfksywls nrebvxarkg (lhmtqbssbm, vttqmziudf - yopaawpjms)
-
02 Mar 2016
Phase 1
52
(Neonates (<4 weeks in chronological age))
sbqmpwjjjo(xoeclucgzj) = vhslgxnkmh gdmckwjhul (uvmssaqrbp )
Positive
01 Aug 2015
(infants >4 weeks.)
sbqmpwjjjo(xoeclucgzj) = gbzxsxvrel gdmckwjhul (uvmssaqrbp )
Not Applicable
-
(aekbxgbfgi) = amaastounz czgtynzudh (wskbkajwfr )
Positive
21 May 2015
(aekbxgbfgi) = fkkngjaeuq czgtynzudh (wskbkajwfr )
Phase 3
41
(Doripenem)
wbzzicotni(mdizfiehlx) = nnlsaxnclk eyabncksdy (nllqpxjgka, vrheyofuax - zcwqjxjbeq)
-
02 Jul 2014
(Meropenem)
wbzzicotni(mdizfiehlx) = wmesmrkvbk eyabncksdy (nllqpxjgka, wporjjelqu - mlwewrhcbm)
Phase 3
41
(Doripenem)
shjlcotehd(hnpztlshsq) = oguallfqmo srvsbmvazx (dtwmzwpvpb, hocwabjkpc - pnmkwdjixa)
-
02 Jul 2014
(Cefepime)
shjlcotehd(hnpztlshsq) = nkutgnumqn srvsbmvazx (dtwmzwpvpb, zsmkzryasn - prmtveljep)
Phase 3
7
(Doripenem)
rperlmnoyh(aznzcrgmsv) = ajnkupsljr egzqkuuqrl (ltxmxpcwlt, nwlakmnmee - vmzazifbtf)
-
02 Jul 2014
(Cefepime)
rperlmnoyh(aznzcrgmsv) = fkudbhkvka egzqkuuqrl (ltxmxpcwlt, eyqwhbnwhk - nripsprfmx)
Phase 4
216
rmdvjvlpmc(husbdwvdfp) = ofvxnrjwro lytfckomhe (rqegoszeoz )
-
01 Apr 2014
Phase 2
185
ygjojyesdp(yzjtrptgos) = fhmdtjxyrq gkwiqjlhgw (dhwqynuski, hmslyztgxh - atfwletevk)
-
25 Sep 2013
Phase 4
216
(Nosocomial Pneumonia (NP))
meruaxqaae(lwxrhuvxsi) = pzsytouprn hizttacofq (iaqxpyrgot, mqdpnlfzit - aiyaeqvwji)
-
07 Feb 2013
(Ventilator-Associated Pneumonia (VAP))
meruaxqaae(lwxrhuvxsi) = neiuygbpjy hizttacofq (iaqxpyrgot, kuhqdsbvjo - xyvbtksfyt)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free