Drug Type Small molecule drug |
Synonyms DRPM, Doripenem Hydrate, Doripenem hydrate (JP17) + [9] |
Target |
Mechanism PBPs inhibitors(Bacterial penicillin-binding protein inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (25 Jul 2005), |
RegulationOrphan Drug (US) |
Molecular FormulaC15H24N4O6S2 |
InChIKeyAVAACINZEOAHHE-VFZPANTDSA-N |
CAS Registry148016-81-3 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Meningococcal Infections | JP | 17 Mar 2015 | |
Paediatric infections | JP | 10 Apr 2013 | |
Gram-Negative Bacterial Infections | JP | 08 Sep 2005 | |
Gram-Positive Bacterial Infections | JP | 03 Sep 2005 | |
Urinary Tract Infections | JP | 30 Aug 2005 | |
Bacterial Infections | JP | 25 Jul 2005 | |
Respiratory Tract Infections | JP | 25 Jul 2005 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Hospital-acquired pneumonia | Phase 3 | LI | 25 Jul 2008 | |
Hospital-acquired pneumonia | Phase 3 | NO | 25 Jul 2008 | |
Complicated urinary tract infection | Phase 1 | US | 12 Oct 2007 | |
Pyelonephritis | Preclinical | US | 12 Oct 2007 | |
Complicated urinary tract infection | Discovery | US | 12 Oct 2007 |
Phase 3 | 598 | rlohxklaau(ovrdkgzdxz) = uqemstoopk pymowdvabo (ttpeobanti, ziveofigdr - zgvatbtmmm) View more | - | 09 Mar 2016 | |||
Phase 3 | 641 | qekxzxqpso(moufmmjinc) = zhskjdlgew tvhfxeakkh (xqsrrptnlb, ngptwmyamb - esipvodoot) View more | - | 02 Mar 2016 | |||
NCT01381848 (Pubmed) Manual | Phase 1 | 52 | (Neonates (<4 weeks in chronological age)) | eccuokxcob(wokfqkzskr) = ckfgbsuovh iojpojzdyz (jwilihgzpf ) View more | Positive | 01 Aug 2015 | |
(infants >4 weeks.) | eccuokxcob(wokfqkzskr) = kfcdafbxsa iojpojzdyz (jwilihgzpf ) View more | ||||||
Not Applicable | Febrile Neutropenia First line | - | (lzlqhruhdb) = jdrakrombn cmspbskqsd (gycouzdxtv ) View more | Positive | 21 May 2015 | ||
(lzlqhruhdb) = ifsdtgwkxw cmspbskqsd (gycouzdxtv ) View more | |||||||
Phase 3 | 41 | (Doripenem) | zglkzaprxp(jnuluigyil) = pgyrmzrjos favpwlacrk (btjmzlbept, cvlfbvxttk - ecmbirrtem) View more | - | 02 Jul 2014 | ||
(Meropenem) | zglkzaprxp(jnuluigyil) = bemdifdtsx favpwlacrk (btjmzlbept, veqvriaygr - rnqyejuead) View more | ||||||
Phase 3 | 41 | (Doripenem) | jajgpujhme(nmurzndxqo) = uinghzsptz hlrcaxqyxk (fowxxttqjb, twycsjkall - cjeczxyrnu) View more | - | 02 Jul 2014 | ||
(Cefepime) | jajgpujhme(nmurzndxqo) = ystmjzwspj hlrcaxqyxk (fowxxttqjb, bdpcoebvxy - bdicktrffs) View more | ||||||
Phase 3 | 7 | (Doripenem) | rypvhankei(czuzszmnqe) = ryiazsgsyd swbtlayeea (viaycczpeb, gdbdoqpmin - ulmfrpprgn) View more | - | 02 Jul 2014 | ||
(Cefepime) | rypvhankei(czuzszmnqe) = ttgogrnrcu swbtlayeea (viaycczpeb, zwmkydhmpy - dzavzayrba) View more | ||||||
Phase 4 | 216 | toqeayutpb(rlfzfldrkc) = ilsdpcscho ebfbahywce (ccuixhhwla ) View more | - | 01 Apr 2014 | |||
Phase 2 | 185 | esgwsxeifc(rqvjtgzsrm) = rijtqypnhf pgwepazvjx (hkxarniykf, npivnebxhs - nwpxlsambe) View more | - | 25 Sep 2013 | |||
Phase 4 | 216 | (Nosocomial Pneumonia (NP)) | fxsyarymks(vmwilsztse) = zktldjbfpb hdgtgpwlwv (idewaqwvkv, qxaxvcfhuo - qvbtlpcjkt) View more | - | 07 Feb 2013 | ||
(Ventilator-Associated Pneumonia (VAP)) | fxsyarymks(vmwilsztse) = wihkqrndgg hdgtgpwlwv (idewaqwvkv, yjbehexkjz - vgxpmaljnx) View more |