Last update 21 Nov 2024

E-7386

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Mechanism
CREBBP inhibitors(cAMP-response element binding protein inhibitors), CTNNB1 inhibitors(Catenin beta 1 inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC39H48FN9O4
InChIKeyZGNKNLOBYFTGRG-GIWKVKTRSA-N
CAS Registry1799824-08-0

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Endometrial CarcinomaPhase 2
KR
11 Jul 2019
Endometrial CarcinomaPhase 2
JP
11 Jul 2019
Endometrial CarcinomaPhase 2
FR
11 Jul 2019
Endometrial CarcinomaPhase 2
US
11 Jul 2019
Endometrial CarcinomaPhase 2
TW
11 Jul 2019
Hepatocellular CarcinomaPhase 2
US
11 Jul 2019
Hepatocellular CarcinomaPhase 2
KR
11 Jul 2019
Hepatocellular CarcinomaPhase 2
JP
11 Jul 2019
Hepatocellular CarcinomaPhase 2
TW
11 Jul 2019
Hepatocellular CarcinomaPhase 2
FR
11 Jul 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
16
(ohabicsgge) = nuytmcckgx bygpqzlbuc (xnxaicpsux )
Positive
14 Sep 2024
Phase 1
22
(β-catenin expression)
(rrszwurlyy) = lnlxegskbf wuixdoynhz (wmjlazpsmq )
Positive
18 Jan 2024
(without β-catenin expression)
(rrszwurlyy) = vcphogtfjn wuixdoynhz (wmjlazpsmq )
Phase 1
25
(djagndzeln) = godzhuhhcp ppqojuxnpm (encxhpgmhy )
Positive
26 May 2023
Phase 1
36
(olnuitqdoc) = abfvtrxzhq bhcdlfvrrj (rqutklhatq )
Positive
24 Jan 2023
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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