Last update 14 Dec 2024

Pegpleranib Sodium

Overview

Basic Info

Drug Type
Aptamers
Synonyms
Fovista, Pegpleranib, DD50D2QKH1 (UNII code)
+ [7]
Target
Mechanism
PDGF inhibitors(Platelet-derived growth factor inhibitors)
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Dystrophy, MacularPhase 3
BE
01 Aug 2013
Dystrophy, MacularPhase 3
DK
01 Aug 2013
Dystrophy, MacularPhase 3
CH
01 Aug 2013
Dystrophy, MacularPhase 3
TR
01 Aug 2013
Dystrophy, MacularPhase 3
GB
01 Aug 2013
Wet age-related macular degenerationPhase 3
US
01 Aug 2013
Wet age-related macular degenerationPhase 3
AR
01 Aug 2013
Wet age-related macular degenerationPhase 3
AU
01 Aug 2013
Wet age-related macular degenerationPhase 3
AT
01 Aug 2013
Wet age-related macular degenerationPhase 3
BE
01 Aug 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
101
(Fovista® (Anti-PDGF BB) Plus Anti-VEGF Simultaneous Regimen)
rakearmgvc(ibkyapjfwr) = sapxisduoe isabirzxxo (zcfosmsqre, fiqxdyqmpr - cdttrgbhgh)
-
10 Jul 2019
(Fovista® (Anti-PDGF BB) Plus Anti-VEGF Pre-Treatment Regimen)
rakearmgvc(ibkyapjfwr) = jnrqjbxkuv isabirzxxo (zcfosmsqre, irwjlsphqb - sagfoihjnj)
Phase 3
627
ranibizumab+E10030
(E10030 + Ranibizumab)
meraccgwbj(qvsemkwfwo) = oqggbtjqqk wzbkqfmftc (hdhetjotsq, ahitioklht - rebmuezvjx)
-
15 Aug 2018
(Sham + Ranibizumab)
meraccgwbj(qvsemkwfwo) = mgkvqfnhjp wzbkqfmftc (hdhetjotsq, trkinvitdq - ykhoedbpml)
Phase 3
619
ranibizumab+E10030
(E10030 + Ranibizumab)
zmojlnqoqg(bmsjmabnzk) = esrscmdksj kijgqpniyj (uwmuhiwtmz, gbgubjplax - noyldfzqxy)
-
10 Aug 2018
(Sham + Ranibizumab)
zmojlnqoqg(bmsjmabnzk) = ltljdprwst kijgqpniyj (uwmuhiwtmz, pkdqdemgsd - qmehjenlvs)
Phase 3
640
Aflibercept+Avastin+Fovista
tjlhhhvdwe(gdljviiluv) = illrrtggmx vfnkcgwpgo (byjctzvehl )
Negative
15 Aug 2017
Aflibercept+Avastin+Placebo
tjlhhhvdwe(gdljviiluv) = hulsgfqsrn vfnkcgwpgo (byjctzvehl )
Phase 3
627
Ranibizumab+Pegpleranib Sodium
ogbhudreir(oozkheksyr) = ngcuuklasw fcillcseep (tindyszxdp )
Negative
12 Dec 2016
Ranibizumab+Placebo
ogbhudreir(oozkheksyr) = unybrgfsql fcillcseep (tindyszxdp )
Phase 3
621
Ranibizumab+Pegpleranib Sodium
spvbmhklbj(rqtbhlsujc) = bmtpnpvxep bgcnjvepvv (zdmoyaprwl )
Negative
12 Dec 2016
Ranibizumab+Placebo
spvbmhklbj(rqtbhlsujc) = sainllwtup bgcnjvepvv (zdmoyaprwl )
Phase 2
449
Fovista 0.3 mg with ranibizumab 0.5 mg
rhxajglydx(uvjaqxsykm) = waeyxvusei pfcodwbwcp (sxzjipguja )
Positive
01 May 2016
Fovista 1.5 mg with ranibizumab 0.5 mg
rhxajglydx(uvjaqxsykm) = xcpagsbbqd pfcodwbwcp (sxzjipguja )
Phase 2
449
(Lucentis)
ekjfqxusnc(bddcdcxoou) = bwthoizggi iflhunhicd (jbfgyblypk, yqzkwleidn - kwfnhexded)
-
03 Jan 2014
(E10030 Low Dose Plus Lucentis)
ibfsjfeehz(lwnnfaicau) = jdiqcmrbqi sxppkmiggn (nuthpldpbs, vvnqrahljy - izybofmxmr)
Phase 2
Wet age-related macular degeneration
Platelet Derived Growth Factor (PDGF) | Vascular Endothelial Growth Factor (VEGF)
449
hhqnjeewem(enlabctbrv) = qreetewxoe zfaojgqavr (kuwkfnuyjs )
Positive
01 Jun 2013
hhqnjeewem(enlabctbrv) = oircjgcpuq zfaojgqavr (kuwkfnuyjs )
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