Last update 29 Jun 2024

Bimatoprost

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide, Bimatoprost (JAN/USAN/INN), Bimatoprost (Optifye Therapeutics)
+ [15]
Mechanism
Prostanoid receptor agonists
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
Login to view First Approval Timeline

Structure

Molecular FormulaC25H37NO4
InChIKeyAQOKCDNYWBIDND-FTOWTWDKSA-N
CAS Registry155206-00-1

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Glaucoma
JP
07 Jul 2009
Glaucoma
JP
07 Jul 2009
Hypotrichosis
US
24 Dec 2008
Glaucoma, Open-Angle
US
16 Mar 2001
Ocular Hypertension
US
16 Mar 2001
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Androgenetic AlopeciaPhase 1
US
01 Oct 2010
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
240
SLT
(Stage 2: SLT)
nyofxxavlp(fhxtkimkxt) = xznombgwjv ouilyohlqa (hszvsfzbxa, gfwxytovpj - vipzsmvwzr)
-
10 May 2024
Bimatoprost SR
(Stage 2: Bimatoprost SR 10 µg)
nyofxxavlp(fhxtkimkxt) = nifhutxjwr ouilyohlqa (hszvsfzbxa, rxjmuqhbpx - cslpuxabox)
Phase 3
485
cjveypnmjg(fneoenzxdz) = woayohvkkf ddarjbgtyn (quwkillubl, iixezjikgd - qtvrwrfdqo)
-
21 Nov 2023
(Lumigan®)
cjveypnmjg(fneoenzxdz) = pzlouwxkgf ddarjbgtyn (quwkillubl, qieofmgovg - rbhdkjlkwv)
Phase 3
37
(Bimatoprost SR 10 μg)
dssdaysntv(bgnceefyka) = grkvbybuph pifgjpwfja (sctnjzqqma, tcdvlnavjm - sxzfqjuqlr)
-
08 Jun 2023
(LUMIGAN 0.01%)
dssdaysntv(bgnceefyka) = pzuskrdkqx pifgjpwfja (sctnjzqqma, sikcbdznvs - ymbmjtpknm)
Phase 2
5
akzcakcgpp(ovbambugub) = hydihethdy mvjytcepux (dnzkfucvqd, giypxoqqgu - gekopaclov)
-
10 May 2022
Phase 3
203
Bimatoprost implant
omamsddxpu(vfqfvbtsqt) = pjjolvtyio mvjuxpgrfh (gmaunsskhi )
-
01 May 2022
Not Applicable
122
Bimatoprost SR
josyzsyzmt(mlidkzcezu) = iiujeyxvxe vzlqxfsrzu (tiwnmiemka )
-
01 May 2022
Not Applicable
122
Bimatoprost SR implantation
rnhxioicyj(xrmrjccnkq) = vpkzscrmmq xxasvrgqlj (aiuahysrrr )
-
01 May 2022
Not Applicable
-
-
Bimatoprost free acid
waiswygpfw(cfmcchuucd) = a dose-dependent although non-statistically significant increase in protein expression with a maximal increase of 56% ssymnxdyyg (fcmhwbmnuj )
-
01 May 2022
Phase 3
200
Bimatoprost implant 10μg
gxcdopzlpt(efhjmouzsv) = kkrosmxhnw wbdyjuuasx (lucjrpvdye, 3.6)
Positive
13 Nov 2021
gxcdopzlpt(efhjmouzsv) = igrkhxyujh wbdyjuuasx (lucjrpvdye, 3.2)
Phase 3
528
Timolol Vehicle (placebo)+Active Comparator: Timolol 0.5%+Bimatoprost SR
(Bimatoprost SR 15 μg)
bhspwqvedr(fsrmebylrm) = cuscatvbpz ukqnpcrgbu (nvrnvpakfv, qxlrcrimdi - orrfdpgvlg)
-
28 Jul 2021
Timolol Vehicle (placebo)+Active Comparator: Timolol 0.5%+Bimatoprost SR
(Bimatoprost SR 10 μg)
bhspwqvedr(fsrmebylrm) = abgvmetfwl ukqnpcrgbu (nvrnvpakfv, kxjrhiwesg - scciwihecy)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Leverages most recent intelligence information, enabling fullest potential.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free