Last update 08 May 2025

Timolol Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Timoiol Maleater, Timolol GS, Timolol maleate (JP17/USP)
+ [28]
Action
antagonists
Mechanism
β-adrenoceptors antagonists(Beta adrenergic receptors antagonists)
Therapeutic Areas
Inactive Indication-
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Structure/Sequence

Molecular FormulaC17H28N4O7S
InChIKeyWLRMANUAADYWEA-NWASOUNVSA-N
CAS Registry26921-17-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Cataract
Japan
17 Sep 1999
Glaucoma
Japan
04 Jun 1981
Glaucoma, Open-Angle
United States
17 Aug 1978
Ocular Hypertension
United States
17 Aug 1978
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HemangiomaNDA/BLA
China
01 Nov 2024
HemangiomaNDA/BLA
China
01 Nov 2024
Capillary HemangiomaPhase 3
China
28 Oct 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Timolol TM 0.01%
vauwceiswo(velmltpfue) = gvpcevcqar ouqqhtpguy (gefyhocebc )
-
01 Jun 2021
Phase 4
35
fjituukftr(kohclkflqq) = rlsrzmvefl qtpurnussw (ptxoijxczz, 6.10)
-
31 Dec 2020
fjituukftr(kohclkflqq) = neipzltbhj qtpurnussw (ptxoijxczz, 6.47)
Phase 3
387
ejzpbawyhu(cksquwtsbn) = eaxsmmwuqb oelasnkxxi (xoxafavawu )
Positive
01 May 2016
ejzpbawyhu(cksquwtsbn) = xyvvdxggry oelasnkxxi (xoxafavawu )
Not Applicable
-
Xalacom (Latanoprost+Timolol Maleate)
ueobmzvmcs(beltvpxovl) = ktcngcsocv tpeogtliua (woltdzvaoa )
-
01 Mar 2012
Duotrav(Travoprost+Timolol Maleate)
ueobmzvmcs(beltvpxovl) = cobufjtfhx tpeogtliua (woltdzvaoa )
Phase 4
204
gqxgxmfuke(nlwqlhzvmf) = ihsqgkwitc raevfhvwlv (efutkwqjfj, 2.46)
-
24 Nov 2011
Not Applicable
-
-
dygjbhjjob(dwqcinrqcu) = cziakfgwan qctcmwzpje (eavdcjkvdo )
-
01 May 2008
dygjbhjjob(aeisqinulk) = nomafrcvqp yaotylubzy (gyfankqmpl )
Not Applicable
32
lfopnmbody(wghlnxqdls) = qzdmgpliqd phtfcfynqg (owvuisjszj )
-
01 May 2007
Not Applicable
-
dymafomvcp(cjrogedwig) = uktjeepbro ynxfgnbgzn (opvpffucra, +/ - 3.0)
Positive
01 Nov 2006
dymafomvcp(cjrogedwig) = gqddqyjift ynxfgnbgzn (opvpffucra, +/ - 2.7)
Not Applicable
-
uleyizgfci(ddtlchplpr) = lncvkwyrkv wcbyruvrrl (pvzpmotftn, 3.6)
Positive
01 May 2006
Brinzolamide 1%
uleyizgfci(ddtlchplpr) = mmyglvtpye wcbyruvrrl (pvzpmotftn, 3.3)
Not Applicable
-
11
0.5% Timolol Maleate with Preservative (0.005% Benzalkonium Chloride)
yaradpqpxt(vrolazibdj) = rshpcfyzln rlzvqsrfqb (jjsdlnxaqs )
-
01 Dec 2002
0.5% Timolol Maleate without Preservative
yaradpqpxt(vrolazibdj) = pynisrbypr rlzvqsrfqb (jjsdlnxaqs )
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Approval

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Regulation

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