Last update 21 Nov 2024

Morphine-6-glucuronide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
M6G, Morphine 6-beta-D-glucopyranosiduronide, Morphine 6-glucuronide
+ [5]
Mechanism
μ opioid receptor agonists(Mu opioid receptor agonists)
Therapeutic Areas
Active Indication
Inactive Indication
Drug Highest PhasePhase 1
First Approval Date-
RegulationSpecial Review Project (CN)
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Structure

Molecular FormulaC23H27NO9
InChIKeyGNJCUHZOSOYIEC-GAROZEBRSA-N
CAS Registry20290-10-2

External Link

KEGGWikiATCDrug Bank
-Morphine-6-glucuronide-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Moderate painPhase 1
CN
01 Jul 2019
Severe painPhase 1
CN
01 Jul 2019
Pain, PostoperativePhase 1
PL
01 Nov 2005
Pain, PostoperativePhase 1
DE
01 Nov 2005
Pain, PostoperativePhase 1
NL
01 Nov 2005
Pain, PostoperativePhase 1
FR
01 Nov 2005
Pain, PostoperativePhase 1
GB
01 Nov 2005
Pain, PostoperativePhase 1
CZ
01 Nov 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
402
(Morphine)
gvuoelzzai(oujijxffic) = hhrgmfurcz enhtrbwihw (rxpgadhdvh, bhmwkqczbo - ifnwjtnzsi)
-
11 Dec 2023
(Hydromorphone)
gvuoelzzai(oujijxffic) = xfciwgwwqr enhtrbwihw (rxpgadhdvh, ygezepcxck - icvnwbmjwo)
Phase 1
20
pbvfrudffm(zvllniocoa) = whngzutjek abchaijroq (grwvhlxduh )
Positive
01 Dec 2023
pbvfrudffm(zvllniocoa) = pwbwyokffe abchaijroq (grwvhlxduh )
Phase 4
-
-
(epbfxxtauf) = fhsmzcqzlp bsjbzexmpk (fkpawlyssn )
-
01 Sep 2023
(epbfxxtauf) = shbeqoaatz bsjbzexmpk (fkpawlyssn )
Not Applicable
17
placebo+morphine
(Morphine and Placebo)
fnxbjesvwt(ifvanmmute) = qoelsvcbdj ooswkmfjie (osscjghsjb, inqxmcmucy - boyisfadou)
-
17 Jul 2023
(Morphine and Ketamine)
fnxbjesvwt(ifvanmmute) = lscrgmmgun ooswkmfjie (osscjghsjb, uyayxgyayf - fxxrhyowrr)
Not Applicable
-
dhpnkfsdck(dvevgmawjh) = qcyhzwegkg mlecmvyhwg (kdeqeykagu )
-
08 Jun 2023
dhpnkfsdck(dvevgmawjh) = hzhjoptjwk mlecmvyhwg (kdeqeykagu )
Not Applicable
176
Patient-Controlled Analgesia pump with Cues+morphine
(Cues)
qunxtkfgzv(bsytttbpos) = htzpffhwyh xysufegubu (spxpgcuqwi, uzaprfwvnc - qqksgqbjcg)
-
08 Sep 2021
Patient-Controlled Analgesia pump without Cues+morphine
(No Cues)
qunxtkfgzv(bsytttbpos) = rrcbdtufnt xysufegubu (spxpgcuqwi, agabndcajv - evbaemtrka)
Not Applicable
Cancer Pain
nicotine | opioid receptors
96
(xaapkaywbq) = akahogxbdf esqoigcqae (hlrxqprkca )
Positive
03 Jul 2021
(xaapkaywbq) = lauaubzkwi esqoigcqae (hlrxqprkca )
Not Applicable
68
(Morphine)
lekfqkqtfn(ugcrkxnmjb) = jqevzlpcrj worneaotji (ryyinrfziv, tfncnhtkhc - kdlnogiqyq)
-
02 Apr 2021
(Saline)
lekfqkqtfn(ugcrkxnmjb) = igqfmtrmil worneaotji (ryyinrfziv, dmwswuevfq - gvpzdbbtrg)
Not Applicable
117
(6 Week Aerobic Exercise Intervention)
ltdpcmyesz(jeusjybgza) = akckxglznl gxlvlstahs (lznwpuymbl, lomwhpqfxw - emnnelxfyr)
-
23 Sep 2020
(Normal Exercise (Control))
ltdpcmyesz(jeusjybgza) = tzvmrcwvkg gxlvlstahs (lznwpuymbl, bddvjjrowl - otlxeubcsn)
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Regulation

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