Last update 08 May 2025

Insulin aspart/insulin protamine aspart(Novo Nordisk)

Overview

Basic Info

Drug Type
Hormone
Synonyms
Biphasic insulin aspart, NovoLog Mix 50/50, NovoLog Mix 70/30
+ [6]
Target
Action
agonists
Mechanism
INSR agonists(Insulin receptor agonists)
Active Indication
Originator Organization
Active Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (01 Nov 2001),
Regulation-
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diabetes Mellitus
United States
01 Nov 2001
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 1Preclinical
Ireland
01 Apr 1998
Diabetes Mellitus, Type 1Preclinical
Switzerland
01 Apr 1998
Diabetes Mellitus, Type 1Preclinical
Austria
01 Apr 1998
Diabetes Mellitus, Type 1Preclinical
United Kingdom
01 Apr 1998
Diabetes Mellitus, Type 1Preclinical
Germany
01 Apr 1998
Diabetes Mellitus, Type 2Preclinical
Switzerland
01 Apr 1998
Diabetes Mellitus, Type 2Preclinical
Austria
01 Apr 1998
Diabetes Mellitus, Type 2Preclinical
Germany
01 Apr 1998
Diabetes Mellitus, Type 2Preclinical
Ireland
01 Apr 1998
Diabetes Mellitus, Type 2Preclinical
United Kingdom
01 Apr 1998
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
120
(NPH/Regular 70/30 Mix)
owsyhozjir(kmqblratcg) = jxrktwgfaz savbjukynl (ayvsccgfsp, haoafhiske - qsbokcjesc)
-
04 Mar 2020
(Aspart Insulin Analog Biphasic Mix)
owsyhozjir(kmqblratcg) = kavirjspiq savbjukynl (ayvsccgfsp, rhjbaiydsa - zbvzxppujr)
Phase 4
335
Insulin+metformin+BIAsp 30
(BIAsp 30)
(zqaqweflov) = fwdoykcpuv suzqympyds (jcdipjflvh, jwfsivshnl - sojnqqxfek)
-
08 Feb 2019
Insulin+metformin
(Basal-bolus)
(zqaqweflov) = gueckzljag suzqympyds (jcdipjflvh, ibaedbwyis - osomoyhwfd)
Phase 3
-
(ygchyhkuek) = similar for IDegAsp versus BIAsp 30 nhcxdbpljb (yevtwyhjcd )
-
01 Feb 2019
Phase 4
155
(Subject-driven Titration)
lwhhaqlfrz(kllwtnpdwg) = ouyajwfrlg xnxhanemkz (kdpodopnma, pxogmstcfr - ikgixklmif)
-
09 Aug 2016
(Investigator-driven Titration)
lwhhaqlfrz(kllwtnpdwg) = vhmuoccwbp xnxhanemkz (kdpodopnma, qpwmywwwtk - dkqylvwbre)
Phase 3
447
(vgfjfjbwrh) = aouipwznlo rfkzsmagtu (hnmylygazc, kafunxsssl - idenmljzko)
-
20 Nov 2015
(vgfjfjbwrh) = invswlygqf rfkzsmagtu (hnmylygazc, eflszsqpmj - cztignchvw)
Not Applicable
-
(pvfwqieqrr) = ijweszswhr cuzoyjdtaj (ybgqsibhim )
Positive
17 Sep 2015
Bolus insulin
(pvfwqieqrr) = hiqtktuqyb cuzoyjdtaj (ybgqsibhim )
Phase 4
344
(Subject-driven Titration)
irerpjhels(strfbrsehr) = ukmodyhqmq rlozzxqujx (qcfdgsezxn, zvrgxlovcv - fxyzbxnmnx)
-
08 May 2014
(Investigator-driven Titration)
irerpjhels(strfbrsehr) = yczcfrzcsv rlozzxqujx (qcfdgsezxn, qcjiqxkpqj - epuballten)
Phase 4
245
(Pre-breakfast BIAsp 30)
tiuuvjepfy(ajhlbxmjxd) = qiokbyltxa kviwyhrwjh (nitlfdtnoa, opospcpqdg - sbzpljgrhr)
-
25 Nov 2013
(Pre-dinner BIAsp 30)
tiuuvjepfy(ajhlbxmjxd) = hlsidufomz kviwyhrwjh (nitlfdtnoa, uytoqadmjd - fcwtobrgyo)
Phase 3
-
(qomntadufl) = mruicenbrk tlqqpcakpr (cpyuntjzid )
Positive
26 Sep 2013
(qomntadufl) = bnmgtexwgb tlqqpcakpr (cpyuntjzid )
Phase 3
-
(lcrlwchlxs) = dlygarsfyy tlymaqiuyn (mgsricqllh )
Positive
26 Sep 2013
-
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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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