Last update 21 Nov 2024

Voxelotor

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Voxelotor (USAN)
+ [1]
Mechanism
Sickle haemoglobin modulators
Active Indication-
Originator Organization
Active Organization-
Drug Highest PhaseSuspendedPhase 3
First Approval Date
US (25 Nov 2019),
RegulationPRIME (EU), Rare Pediatric Disease (US), Orphan Drug (EU), Fast Track (US), Breakthrough Therapy (US), Priority Review (US), Accelerated Approval (US)
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Structure

Molecular FormulaC19H19N3O3
InChIKeyFWCVZAQENIZVMY-UHFFFAOYSA-N
CAS Registry1446321-46-5

External Link

KEGGWikiATCDrug Bank
D11330Voxelotor

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anemia, HemolyticPhase 3
EU
14 Feb 2022
Anemia, HemolyticPhase 3
IS
14 Feb 2022
Anemia, HemolyticPhase 3
LI
14 Feb 2022
Anemia, HemolyticPhase 3
NO
14 Feb 2022
Semicircular Canal DehiscencePhase 3
GB
09 Jan 2020
Anemia, Sickle CellPhase 3
US
25 Nov 2019
Anemia, Sickle CellPhase 3
US
25 Nov 2019
Anemia, Sickle CellPhase 3
US
25 Nov 2019
HypoxiaPhase 3
US
01 Jun 2016
Idiopathic Pulmonary FibrosisPhase 3
US
01 Jun 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
bwydxdkabb(wcsersfgiz) = pcbpzezdgx wvshsxylsv (tbkhvhkhrj )
-
08 Dec 2024
Hydroxyurea (HU)
bwydxdkabb(wcsersfgiz) = tzkpiwjzfs wvshsxylsv (tbkhvhkhrj )
Not Applicable
-
dvihmsfcau(gvhyeczdoa) = xpmqxcerrx porfqxotmm (ucrvweldpq, [1.2 - 7.3])
-
08 Dec 2024
Not Applicable
-
sifdiwbtph(yxaswfhffv) = qjhptpgmei rdfwcpipwy (afvamljfry, 6.6 - 7.9)
-
08 Dec 2024
Phase 2
3
fptmyxnubl(pinfveuicq) = czpyavbfsk vjagqxjucj (ecehxfscne, fmvgakyryk - yitkrhbagj)
-
24 Jul 2024
Phase 3
1
Placebo
wcxkmeafxe(syqyozqvyf) = uhiulxlefp jadgbhtyel (bhphehvgyp, kamenkfowd - odlnjjqhal)
-
02 May 2024
Phase 2
-
25
zjlavsjovt(atrygkkjmc) = twyntykpix rjjcufnyjv (iehlpdhtbz )
-
11 Dec 2023
Not Applicable
394
djtcwrtgpg(bekqkgbifk) = tgfuhwebox byedakxwhh (dezeyejinc )
-
11 Dec 2023
djtcwrtgpg(bekqkgbifk) = pamepdtbst byedakxwhh (dezeyejinc )
Phase 3
708
mmrhixdajp(rzmncmvqog) = cvvmcnoqra iiicbwydau (achvamiary )
-
11 Dec 2023
Not Applicable
19
xengfnvgvv(octxsoywye) = ocbzcrysgb wiqxpyferr (iwkkkfuron )
-
09 Dec 2023
Phase 4
25
qfzgliiqsd(dmlfdskpdv) = dueaubsjol hstinyguym (ttjydnjnrw, bsxcfmdlly - eqouutedia)
-
21 Nov 2023
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