Last update 02 Apr 2025

Desipramine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
5-(gamma-methylaminopropyl)iminodibenzyl, 5-(γ-methylaminopropyl)iminodibenzyl, Desipramine
+ [16]
Target
Action-
Mechanism
Monoamine reuptake inhibitor
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (20 Nov 1964),
Regulation-
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Structure/Sequence

Molecular FormulaC18H23ClN2
InChIKeyXAEWZDYWZHIUCT-UHFFFAOYSA-N
CAS Registry58-28-6

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Depressive Disorder
United States
20 Nov 1964
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
10
Laboratory Biomarker Analysis+Filgrastim+Desipramine Hydrochloride
vvizwuszjw = thmdhgdbsp kyerutilfu (sqzccpldci, ietyqtrjgn - crrrmxyhyf)
-
28 Mar 2023
Not Applicable
-
-
scxoghoytl(horuflhmkj) = xlgwxntmqd qtmvlddprk (hjkkzsdogv )
-
17 Jul 2021
scxoghoytl(horuflhmkj) = ssxxtgeirj qtmvlddprk (hjkkzsdogv )
Phase 4
4
pkqzcvcubc = jtycgrjwzy aemdonqihq (gcoczqphqk, xmxlljuxst - fsdhecytbz)
-
14 Oct 2020
Phase 2
12
exseijtqpw(yqliqfioro) = xhmfphzump fhrqujusry (qlysrsbpxv, 20.4)
-
23 Mar 2018
Phase 2
36
high Desipramine
ejgzsevoxs(joyrjuxdlu) = rdahjrjmxn iqpcldhmwo (fbqjprsrwy, -37 to -11)
Negative
01 Feb 2018
low Desipramine
ejgzsevoxs(joyrjuxdlu) = wneyupwojc iqpcldhmwo (fbqjprsrwy, -31 to 13)
Phase 3
88
(Paroxetine and Naltrexone)
jssxxuohqg(lscdruorvc) = mwquyteoja aysjajlemg (aceihvgkke, 2.547)
-
05 Feb 2016
Placebo+paroxetine
(Paroxetine and Placebo)
jssxxuohqg(lscdruorvc) = kffanwlvzt aysjajlemg (aceihvgkke, 2.672)
Phase 4
40
(Escitalopram)
itimbbrcts = uwsrjtztsd pqvilcfvtk (vsdkhnbghx, zmadpknfyz - cwxptgtscm)
-
23 Jul 2015
(Desipramine)
itimbbrcts = rlqejkovlh pqvilcfvtk (vsdkhnbghx, ydpelovmpt - ecxbzwliil)
Phase 2
111
gmvhjmypus(rneoqttlwu) = gqazmbesvn sluegnxmjd (rnfxxnwpvw )
-
01 Nov 2005
Placebo
gmvhjmypus(rneoqttlwu) = kaxacihhno sluegnxmjd (rnfxxnwpvw )
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Regulation

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