Last update 26 May 2026

CMS-D001

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CMS-D001
Target
TYK2
Action
inhibitors
Mechanism
TYK2 inhibitors(Tyrosine-protein kinase 2 inhibitors)
Therapeutic Areas
Immune System DiseasesSkin and Musculoskeletal DiseasesCongenital Disorders+ [1]
Active Indication
Plaque psoriasisModerate Atopic DermatitisSevere Atopic Dermatitis+ [4]
Inactive Indication-
Originator Organization
Hainan Dermavon Pharmaceutical Technology Co., Ltd.
Active Organization
Hainan Dermavon Pharmaceutical Technology Co., Ltd.China Medical System Holdings Ltd.China Medical System Holdings Ltd.Shenzhen Kangzhe Biotech Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2/3
First Approval Date-
Regulation-
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Related

12
Clinical Trials associated with CMS-D001
ChiCTR2600123830
/ Not yet recruitingPhase 1IIT
A Single-Center, Open-Label, Self-Controlled Clinical Study to Evaluate the Drug-Drug Interaction (DDI) of CMS-D001 with Itraconazole or Rifampicin in Healthy Participants
ChiCTR2600123119
/ Not yet recruitingNot ApplicableIIT
A single-center, randomized, open-label, two-period, two-sequence crossover clinical study to evaluate the effect of food on the pharmacokinetic characteristics of CMS-D001 tablets in healthy participants.
NCT07465120
/ Not yet recruitingPhase 2
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase Ⅱ Clinical Study to Evaluate the Efficacy and Safety of CMS-D001 in Adult Patients With Moderate to Severe Atopic Dermatitis
100 Clinical Results associated with CMS-D001
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100 Translational Medicine associated with CMS-D001
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100 Patents (Medical) associated with CMS-D001
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100 Deals associated with CMS-D001
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Plaque psoriasisPhase 3
China
Hainan Dermavon Pharmaceutical Technology Co., Ltd.
03 Mar 2026
Moderate Atopic DermatitisPhase 2
China
Hainan Dermavon Pharmaceutical Technology Co., Ltd.
19 Jan 2026
Severe Atopic DermatitisPhase 2
China
Hainan Dermavon Pharmaceutical Technology Co., Ltd.
19 Jan 2026
Dermatitis, AtopicPhase 1
China
China Medical System Holdings Ltd.China Medical System Holdings Ltd.
-
PsoriasisPhase 1
China
China Medical System Holdings Ltd.China Medical System Holdings Ltd.
-
Colitis, UlcerativeIND Approval
China
Shenzhen Kangzhe Biotech Co., Ltd.
25 May 2026
Crohn DiseaseIND Approval
China
Shenzhen Kangzhe Biotech Co., Ltd.
25 May 2026
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Clinical Trial

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Approval

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Regulation

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