Last update 21 Nov 2024

Nalfurafine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Nalfurafine, Nalfurafine hydrochloride (JAN/USAN), Nopicor
+ [10]
Mechanism
κ opioid receptor agonists(Kappa opioid receptor agonists)
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
JP (21 Jan 2009),
RegulationOrphan Drug (KR)
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Structure

Molecular FormulaC28H32N2O5
InChIKeyXGZZHZMWIXFATA-UEZBDDGYSA-N
CAS Registry152657-84-6
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pruritus
JP
21 Jan 2009
Pruritus
JP
21 Jan 2009
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic liver diseasePhase 3
CN
13 Oct 2023
Chronic liver diseasePhase 3
CN
13 Oct 2023
Chronic liver diseasePhase 3
CN
13 Oct 2023
PruritusPhase 3
CN
17 Dec 2021
Uremic pruritusPhase 3
CN
07 Sep 2020
Uremic pruritusPhase 2
CN
07 Sep 2020
Kidney Failure, ChronicPhase 2
US
01 Sep 2012
Kidney Failure, ChronicDiscovery
US
01 Sep 2012
Cancer PainDiscovery
US
--
Dermatitis, AtopicDiscovery
JP
--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
45
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-
09 Feb 2022
lhfejallzb(xdighkxlbm) = gfdqcyogdy iuryndqlyb (gtrotcvqye, kjnbmculgn - gfiwaxhkzx)
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Regulation

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