Yanhouning Oral Liquid

Healthy volunteers were selected as subjects, and starting from a safe initial dose, a dose escalation test was conducted to observe the safety and tolerability of the Yanhou Ning oral liquid in humans. The concentrations of matrine, oxymatrine, cytisine, N-methyl cytisine, solanine, chaconine, chaconine, β-chaconine, and α-chaconine in plasma were tested after healthy people took the Yanhou Ning oral liquid, and their exposure in humans was studied to provide data support for the formulation of the dosing regimen and quality control for the Phase II clinical trial of this product.