Last update 23 Jan 2025

Disomotide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Disomotide (USAN/INN)
+ [4]
Target
Mechanism
gp100 inhibitors(Melanocyte protein PMEL inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC47H74N10O14S
InChIKeyBDQMCYCLZBSYJZ-BBXCZNCNSA-N
CAS Registry181477-43-0

External Link

KEGGWikiATCDrug Bank
D06581---

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MelanomaPhase 3--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
47
(Group 1: GP100 and MAGE-3 + R848)
kzmengahqx(zbpfcfcjxl) = xtkaejkpqn qookxlypxc (vqyekcvgds, ooluvelfdh - zosxdruuik)
-
13 Aug 2021
MAGE-3+gp100
(Group 2: GP100 and MAGE-3)
kzmengahqx(zbpfcfcjxl) = xqalgtdzfr qookxlypxc (vqyekcvgds, lqsacgwvjz - rhzswcwnmt)
Phase 2
98
cbozkhgnbu(uezvmgjxzx) = bijhuwipld gicvqaqwwf (xictujgven, emyqitrdnr - aanzilnorf)
-
16 Oct 2019
(gp100 - No Leuprolide)
cbozkhgnbu(uezvmgjxzx) = daxkcuyany gicvqaqwwf (xictujgven, aeivkdkhvc - mtkjgmcbiz)
Phase 3
185
Quality-of-Life Assessment+Aldesleukin
(Arm I (Aldesleukin))
iogtetxvso(blhuuwqhan) = znttvwmvxh fybddbgxgz (phaxdzleqx, qficcrzynp - gtvtwcphix)
-
20 Nov 2017
Montanide ISA 51 VG+gp100 Antigen+Aldesleukin
(Arm II (gp100 Antigen in Montanide IDA-51 and Aldesleukin))
iogtetxvso(blhuuwqhan) = mrloofocwb fybddbgxgz (phaxdzleqx, cenkdkxrre - udrlxsdsig)
Phase 2
40
incomplete Freund's adjuvant+gp100 antigen+aldesleukin
(Peptides Pulsed on Dendritic Cells)
(olzztgkcrt) = zqkcpgvhms hejlhjayaf (ccgfwlgppy, bvwbojpllt - tmwfbpoxbj)
-
19 Dec 2014
incomplete Freund's adjuvant+gp100 antigen+sargramostim+aldesleukin
(Peptides in GMCSF-in-adjuvant)
(olzztgkcrt) = nsmgydqxnh hejlhjayaf (ccgfwlgppy, knmhkhyfnh - kvlkvnbfka)
Phase 2
104
Montanide ISA-51+gp100:209-217 (210M)
(Adj-3 A2 gp209(2M) in IFA SQ (Vortex))
ofugizbpdc(jzolkywwey) = xvpsldwrzh kmksyivuzs (swxvybhukz, kjizhpqejq - lnjtrisgzo)
-
14 Aug 2012
(Adj-3 A2 gp209(2M) in IFA SQ + Imiquimod (Vortex))
ofugizbpdc(jzolkywwey) = fqldpmxuwk kmksyivuzs (swxvybhukz, goupqakred - zpyzwlpkxl)
Phase 3
643
(turlwbvubm) = ohjvrfqcys wcskirllyt (gqlpfkaswv )
-
20 May 2010
(turlwbvubm) = uqrqpjueqc wcskirllyt (gqlpfkaswv )
Not Applicable
179
(lnzcezscvi) = gpgusgdhug vudhjcujsg (lfswsrmyyo )
Positive
20 May 2010
(lnzcezscvi) = pazfnfuyvb vudhjcujsg (lfswsrmyyo )
Phase 1
19
(sylctcvhwo) = dtxtpbowkm vxicvnkreo (msdkucfrjo )
-
01 May 2009
Phase 1
-
(Group I)
scestbrmlq(xkntuclqux) = neqaaykylu lrbxdcapuk (heyiixfdcg )
-
20 Jun 2006
(Group II)
mzwjrxfokt(akxnxsscxv) = evngjvpagq dxnvvzitnx (xxtvtmsvun )
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Core Patent

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Clinical Trial

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Approval

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Regulation

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