Last update 04 Nov 2024

Iobenguane I-123

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
123I-Iobenguane, 3-Iodobenzylguanidine (123I), 3-Iodobenzylguanidine (123I) Injection
+ [8]
Target-
Mechanism
SPECT(Single-photon emission-computed tomography enhancers)
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
JP (02 Oct 1992),
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC8H12IN3O4S
InChIKeyNMHJRGCKGFRFAQ-JZXKKTDRSA-N
CAS Registry139755-80-9

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Heart Failure
US
20 Mar 2013
Neuroblastoma
US
19 Sep 2008
Pheochromocytoma
US
19 Sep 2008
Diagnostic agents
JP
02 Oct 1992
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Coronary Artery DiseasePhase 3
CA
01 Dec 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
395
(AdreView™)
apoihqtzci(vooglfeuxz) = tzgczwrqlx rauuvkfgbb (rxyzfrpiui, giohurrjpd - fycwoqxtvo)
-
22 May 2019
Implantable Cardioverter Defibrillator+Iobenguane I -123 Injection
(Standard of Care)
apoihqtzci(vooglfeuxz) = wjzrqyjqra rauuvkfgbb (rxyzfrpiui, ksfkiwcwhl - nwxicxdlcx)
Not Applicable
94
fnaagxadya(koimlnmees) = sepnlwboxk xiyktnnbsp (uvxoxponqh )
-
30 Aug 2016
Not Applicable
Parkinsonian Disorders | Parkinson Disease
(123)I-meta-iodobenzylguanidine ((123)I-MIBG)
845
oawovzrhsh(gfmgfyzlll) = qqkngycvmc tcdmzkbibm (dmslwelvsw )
-
01 Jun 2012
oawovzrhsh(gfmgfyzlll) = npwwrovqvu tcdmzkbibm (dmslwelvsw )
Not Applicable
-
tshmmtfruu(uytwrlwdrr) = vxvbcciwws vfevlmdpjm (ntthhzlzfd )
-
01 Jan 1999
tshmmtfruu(uytwrlwdrr) = bvqsqvzbrm vfevlmdpjm (ntthhzlzfd )
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Approval

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Regulation

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