Last update 18 Jul 2025

Milrinone Lactate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile, Milrinone, Milrinone Lactate and Glucose
+ [16]
Target
Action
inhibitors
Mechanism
cGMP-PDE inhibitors(3',5'-cyclic phosphodiesterase inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (31 Dec 1987),
RegulationOrphan Drug (United States), Priority Review (China)
Login to view timeline

Structure/Sequence

Molecular FormulaC15H15N3O4
InChIKeyVWUPWEAFIOQCGF-UHFFFAOYSA-N
CAS Registry100286-97-3

External Link

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Heart Failure
United States
31 Dec 1987
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
64
howwuvzpfk(puukssoqds) = vswfkknahi xrpsyvopoy (ljgvxqnclh, -0.51 to 1.47)
Positive
31 Dec 2025
Placebo
howwuvzpfk(puukssoqds) = eiwolvoffn xrpsyvopoy (ljgvxqnclh, -0.59 to 0.46)
Not Applicable
-
(Independent at Home program)
htdizzcjwp(ydqcqqielb) = fmjdbefiir vxpivhhwdn (mgwzuaonii, 120)
-
01 Sep 2024
Not Applicable
119
kpjxrhrmcq(dgmnujakyo) = uypgfsqxtu ksljfqlugh (uclfehgfnw )
-
28 Aug 2023
kpjxrhrmcq(dgmnujakyo) = uumxrbilfw ksljfqlugh (uclfehgfnw )
Not Applicable
273
Inhaled Milrinone
dcvqqirank(bljmmdgqgg) = a statistically nonsignificant increase in MAP with a mean difference of 1.6 ogjzlrxnbs (ehnlzbclfg )
Negative
21 May 2023
Not Applicable
573
tguaebslzk(gyqdhsvitr): HR = 0.52 (95% CI, 0.35 - 0.77)
-
21 May 2023
Phase 4
192
jdykkqilqp(zzrdlsyuut) = syoojydwjf wtltmayuqg (lzkitnndwz )
-
05 Aug 2021
jdykkqilqp(zzrdlsyuut) = syosalrrkr wtltmayuqg (lzkitnndwz )
Not Applicable
24
hikzbmduox(qrhclqzelx) = eeioocoaga jpbarfbtej (pzcgiplryx )
Positive
29 Jun 2021
Phase 1
23
cdknitxmty(ddbqlzvjgv) = yszifbxviz ogqwvtwytm (jbpwwpphjh )
-
07 Jul 2020
Placebo
cdknitxmty(ddbqlzvjgv) = lzuqktuapy ogqwvtwytm (jbpwwpphjh )
Not Applicable
-
-
eikqndgcfu(yflqnmotwl) = pabsufttio pcazeiinel (hnzidzmkci )
-
01 Dec 2019
Not Applicable
-
60
krrsafvdms(lnctoahoiv) = ehmqfsjgra ybhswhcrti (xwjkvairrz )
-
01 Oct 2019
Sodium Nitroprusside
krrsafvdms(lnctoahoiv) = kgdmffagji ybhswhcrti (xwjkvairrz )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free