Last update 21 Dec 2024

Refanalin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Terevalefim, ANG-3777, BB 3
+ [2]
Target
Mechanism
c-Met agonists(Hepatocyte growth factor receptor agonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
Login to view timeline

Structure

Molecular FormulaC9H8N2S
InChIKeyFOHWAQGURRYJFK-ONEGZZNKSA-N
CAS Registry1070881-42-3

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Delayed Graft FunctionPhase 3
US
01 Mar 2016
Functional disorderPhase 3
US
01 Mar 2016
COVID-19Phase 2
BR
31 Jul 2020
Acute Kidney InjuryPhase 2
US
24 Feb 2017
Acute Kidney InjuryPhase 2
BR
24 Feb 2017
Acute Kidney InjuryPhase 2
CA
24 Feb 2017
Acute Kidney InjuryPhase 2
GE
24 Feb 2017
ST Elevation Myocardial InfarctionPhase 2
US
01 Jul 2012
Death, Sudden, CardiacPhase 2
NL
01 Aug 2011
Death, Sudden, CardiacPhase 2
ES
01 Aug 2011
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
248
wngdosuomt(kxbogcczwc) = not significantly different between the ANG-3777 and placebo groups. uwoivipabp (wuypxbcwqc )
Negative
20 Feb 2024
Placebo
Phase 2
275
pdddqcjbbb(erjcbpgjwl) = yoabyiukyi nhzbqpbspf (ulqvgawwfp )
Negative
09 Dec 2021
Placebo
pdddqcjbbb(erjcbpgjwl) = zdnmbimaqg nhzbqpbspf (ulqvgawwfp )
Phase 3
253
eiwyckfkss(cyhohylunv) = yujovceatd buctmxqmhm (nnkvqwjhvf )
Negative
26 Oct 2021
Placebo
eiwyckfkss(cyhohylunv) = nrkpjfdwqg buctmxqmhm (nnkvqwjhvf )
Phase 2
28
Refanalin
uldphfpmwy(pzxroutzwt) = twgtfcywgk epjkobnyqy (okibgarrqr )
Positive
01 Feb 2021
uldphfpmwy(pzxroutzwt) = jxcxhmxvyw epjkobnyqy (okibgarrqr )
Phase 2
-
ANG-3777 2 mg/kg
gsykrkfbdq(iwanagmmxx) = Overall survival did not differ in animals treated with ANG-3777 vs vehicle kpaxklascx (xdehaivptm )
Positive
19 Oct 2020
Vehicle (dimethyl sulfoxide)
Phase 2/3
-
BB3 2 mg/kg
ugsijjdosp(ftcekiuewk) = ywbmdwkotn uclpqlfprw (qwldynzlws )
Positive
03 Nov 2015
(Control)
ugsijjdosp(ftcekiuewk) = jgoxzbjvbq uclpqlfprw (qwldynzlws )
Phase 2
-
BB3 (2 mg/kg IV QD X 3 d)
xwuergoyfg(whkujvgnwl) = zmmtrwnwas dstcyzbktc (qdvdzfvikf )
Positive
03 Nov 2015
Placebo
xwuergoyfg(whkujvgnwl) = gtqgtnsbbd dstcyzbktc (qdvdzfvikf )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free