Last update 21 Nov 2024

Refanalin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Terevalefim
+ [2]
Target
Mechanism
c-Met agonists(Hepatocyte growth factor receptor agonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC9H8N2S
InChIKeyFOHWAQGURRYJFK-ONEGZZNKSA-N
CAS Registry1070881-42-3

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Kidney InjuryPhase 3
GE
24 Feb 2017
Acute Kidney InjuryPhase 3
US
24 Feb 2017
Acute Kidney InjuryPhase 3
CA
24 Feb 2017
Delayed Graft FunctionPhase 3
US
01 Mar 2016
Functional disorderPhase 3
US
01 Mar 2016
ST Elevation Myocardial InfarctionPhase 3
US
01 Jul 2012
Death, Sudden, CardiacPhase 3
NL
01 Aug 2011
Death, Sudden, CardiacPhase 3
ES
01 Aug 2011
Death, Sudden, CardiacPhase 3
GB
01 Aug 2011
Renal injuryPhase 3
US
01 Feb 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
248
(epozpzwsvj) = not significantly different between the ANG-3777 and placebo groups. qmrgafiips (zqwbjllsrp )
Negative
20 Feb 2024
Placebo
Phase 2
275
(ytkxvgrdrb) = pgwwycxisc ucbcqrmuke (rrlyxbfate )
Negative
09 Dec 2021
Placebo
(ytkxvgrdrb) = gvaxhkdnjh ucbcqrmuke (rrlyxbfate )
Phase 3
253
(pldnweypol) = hgzuybujqd jjchvxeubg (pllxsvbcpk )
Negative
26 Oct 2021
Placebo
(pldnweypol) = jtrwdjkbss jjchvxeubg (pllxsvbcpk )
Phase 2/3
-
(mosravqwoz) = ksaasqsden pnxvyprzyr (vcmvdtktyq )
Positive
03 Nov 2015
(mosravqwoz) = dfntmpcqyd pnxvyprzyr (vcmvdtktyq )
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Approval

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Regulation

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