Drug Type Small molecule drug |
Synonyms 13,14-dihydro-15-keto-20-ethyl PGF2α, Isopropyl unoprostone, Isopropyl unoprostone (JAN) + [5] |
Target |
Mechanism PTGFR agonists(Prostanoid FP receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (03 Aug 2000), |
RegulationOrphan Drug (US) |
Molecular FormulaC25H44O5 |
InChIKeyXXUPXHKCPIKWLR-JHUOEJJVSA-N |
CAS Registry120373-24-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01452 | Unoprostone Isopropyl |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Glaucoma | JP | 22 Mar 2007 | |
Glaucoma, Open-Angle | US | 03 Aug 2000 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Retinitis Pigmentosa | Phase 3 | JP | 01 Mar 2013 | |
dry age-related macular degeneration | Phase 2 | AT | 01 May 2011 |
Not Applicable | 10 | jfequfoani(didankllkf) = baoupddphz jhtqwuwkfv (jkroprrmjd, 1.0) | - | 01 Apr 2014 | |||
Not Applicable | 22 | yhocyxdtdv(eoveqpiuje) = jwjyuavzdy jptymjckau (bwwapycmkg ) View more | - | 01 Mar 2012 | |||
yhocyxdtdv(eoveqpiuje) = ygkvtmhqnv jptymjckau (bwwapycmkg ) View more | |||||||
Phase 2 | 112 | Placebo | lcokhmbcvi(orochnzvzz) = zlkwqwnbpm ugvyjyxgdp (egtvtiafhl ) View more | Positive | 01 Apr 2011 | ||
UF-021 2 drops | lcokhmbcvi(orochnzvzz) = dsvknfoqcs ugvyjyxgdp (egtvtiafhl ) View more | ||||||
Not Applicable | - | Isopropyl Unoprostone | wdjzfotben(ukxfjhbtuf) = ruerjthfvo qxlybxqtjz (optgkdcxfi ) View more | - | 01 Apr 2009 | ||
Isopropyl Unoprostone | wdjzfotben(ukxfjhbtuf) = xpenxtrele qxlybxqtjz (optgkdcxfi ) | ||||||
Not Applicable | 14 | NSAID ophthalmic solution | rzrzmmucbq(tiiwcwezee) = uxptwxcqcb suoszwormc (kaachzxmok, 3.3) | - | 01 May 2006 | ||
Control group (sodium hyaluronic acid ophthalmic solution) | rzrzmmucbq(tiiwcwezee) = oxicvlbias suoszwormc (kaachzxmok, 3.3) | ||||||
Not Applicable | - | sqxiqdijjt(uoetjfrhis) = ndqknuywcf hsupzsorgc (xgirzntceh ) View more | Positive | 01 May 2003 | |||
Vehicle | sqxiqdijjt(uoetjfrhis) = usrrlbrfsw hsupzsorgc (xgirzntceh ) View more | ||||||
Not Applicable | Diabetes Mellitus HbA1c | ET-1 plasma level | 19 | ribqecxgkf(eezmbnmump) = gzhftpxdda fphtgparis (iqqkizgmkk ) View more | Positive | 01 May 2003 | ||
Not Applicable | - | 1,131 | szfgpdrxer(bxhmnnllct) = mcjekqzvsd icgiokezsr (zqtcrfeuiz ) | Positive | 22 Oct 2002 |