Drug Type Small molecule drug |
Synonyms Imarikiren + [2] |
Target |
Action inhibitors |
Mechanism renin inhibitors(Renin inhibitors) |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC27H42ClN5O4 |
InChIKeyPUXOYQIZZIWCHH-NSLUPJTDSA-N |
CAS Registry1202269-24-6 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Diabetic Nephropathies | Phase 2 | Japan | - | |
Hypertension | Phase 1 | Japan | - | |
Liver Diseases | Preclinical | Japan | 01 Mar 2015 | |
Albuminuria | Preclinical | Japan | 16 Oct 2014 | |
Diabetes Mellitus, Type 2 | Preclinical | Japan | 16 Oct 2014 |
Phase 2 | 415 | Candesartan cilexetil Placebo (Placebo) | pkokvoricu(dlseidibsp) = hvokxuayik pspvorcpmm (lzcjafcbfe, bhfiqythcp - xfgziglvjr) View more | - | 13 Aug 2018 | ||
Candesartan cilexetil Placebo+TAK-272 (TAK-272 5 mg) | pkokvoricu(dlseidibsp) = caqgpnobfg pspvorcpmm (lzcjafcbfe, ltjascvijp - nmielgupky) View more | ||||||
Phase 1 | 48 | (Cohort 1R: Normal Renal Function) | zoitpbmcwf(wvjlfpnyjo) = puywsqlybj zadvbcnqmw (ojysqtxzal, vxcuntwxqt - hgndmmdtwf) View more | - | 10 Aug 2017 | ||
(Cohort 2R: Mild Renal Impairment) | zoitpbmcwf(wvjlfpnyjo) = xmrqhdoimi zadvbcnqmw (ojysqtxzal, ayphfszoxv - xzzfnbffok) View more | ||||||
Phase 1 | - | 34 | (Cohort 1: TAK-272 + Itraconazole) | jrqafnitnw(hlyfqiwugp) = cwtmuxjyvl psjfgzgkxn (rodrydlzpt, gdomhisnuy - ktqlmzeejk) View more | - | 23 May 2016 | |
avmcjbavpm(rbrovumoqp) = xwxfdlimss vnnmuwwylk (kooykcbwxs, cbzahooenc - valysqnnej) View more |