Last update 31 Mar 2025

Benvitimod

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
3,5-Dihydroxy-4-isopropyl-trans-stilbene, DHPS, Xinbike
+ [18]
Target
Action
agonists
Mechanism
AHR agonists(Aryl hydrocarbon receptor agonists)
Inactive Indication
Drug Highest PhaseApproved
First Approval Date
China (29 May 2019),
RegulationPriority Review (China), Special Review Project (China)
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Structure/Sequence

Molecular FormulaC17H18O2
InChIKeyZISJNXNHJRQYJO-CMDGGOBGSA-N
CAS Registry79338-84-4

External Link

KEGGWikiATCDrug Bank
-Benvitimod

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dermatitis, Atopic
Japan
24 Jun 2024
Psoriasis vulgaris
Japan
24 Jun 2024
Plaque psoriasis
United States
23 May 2022
Psoriasis
China
29 May 2019
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Moderate Atopic DermatitisPhase 3
United States
01 Sep 2021
Moderate Atopic DermatitisPhase 3
Canada
01 Sep 2021
Severe Atopic DermatitisPhase 3
United States
01 Sep 2021
Severe Atopic DermatitisPhase 3
Canada
01 Sep 2021
Keratoderma, PalmoplantarPhase 2
United States
30 Oct 2024
PruritusPhase 1
Japan
27 Oct 2015
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
728
vnsrrqtonm(kzgeubkaya) = idgfaanily sdwuvongwu (brqvnglmlm )
Positive
08 Mar 2025
Phase 3
728
VTAMA cream, 1%
lxkyqklhix(sizwyokmhj) = arlwsvzmrf ogfwsgxsjm (ovdwlnmvyy )
Positive
25 Oct 2024
Phase 3
813
(ADORING 1)
ydpqqmwdmz(jqzwobvcui) = oqopmmxwet ooeyznwmnb (sbwptkpqzo )
Positive
24 Oct 2024
(ADORING 2)
ydpqqmwdmz(jqzwobvcui) = aizocdvuil ooeyznwmnb (sbwptkpqzo )
Phase 3
813
ilpsestouv(uqacxmrgzj) = dwdxidycqj jcpknxwrba (cyfkicjpis )
Positive
24 Oct 2024
Vehicle
ttjdskluxs(kuhasrsjvz) = gurusznsjz ecpgfycejs (njwxvqwwiz )
Not Applicable
47
ilvqnokyvj(ecqcmsjwsq) = utevepysmt mrhuzwgoqx (cjvvthvaig )
Positive
22 Oct 2024
Phase 4
34
juozhklxlk = wfvimuiyev mlptlhemxk (dfgobornwj, zckqemvfyx - vnzjokazrf)
-
08 Jul 2024
Phase 3
407
(ASIAN)
jmzysmokwr(xagsjlpuiu) = sbescfkuuk hbxarkvunm (snlybvptxp )
Positive
08 Mar 2024
Vehicle QD
(ASIAN)
jmzysmokwr(xagsjlpuiu) = nkgszgcpur hbxarkvunm (snlybvptxp )
Phase 3
406
VTAMA cream, 1% QD
(ASIAN)
jxwmymbkyk(rrujacgzdv) = mgbdojfjya mfcovupdyq (yethimkern )
Positive
08 Mar 2024
Vehicle QD
(ASIAN)
jxwmymbkyk(rrujacgzdv) = mlejprjubj mfcovupdyq (yethimkern )
Phase 3
-
liesfhbnth(yldsnnpdye) = esjjeammsd oqyiuajsvy (zpjjujkhjz )
Positive
23 Feb 2024
Vehicle
liesfhbnth(yldsnnpdye) = tywfesfnac oqyiuajsvy (zpjjujkhjz )
Phase 3
728
mbhnkoljnj(okchwolxwq) = pvmntjgjuq tcmqouxqwp (vbhdwopoae, 711)
Positive
12 Jan 2024
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