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Last update 26 Oct 2025
NS-041
Last update 26 Oct 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms NS 041 |
Target |
Action agonists, stimulants |
Mechanism Kv7.2 agonists(Voltage-gated potassium channel subunit Kv7.2 agonists), Kv7.3 stimulants(Potassium voltage-gated channel subfamily KQT member 3 stimulants) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Related
3
Clinical Trials associated with NS-041CTR20251874
一项评估NS-041作为局灶性癫痫添加治疗的安全性和有效性的随机、双盲、安慰剂对照、多中心的Ⅱ期临床试验
[Translation] A randomized, double-blind, placebo-controlled, multicenter Phase II clinical trial to evaluate the safety and efficacy of NS-041 as an add-on treatment for focal epilepsy
CTR20244520
评价在中国健康成年人中伊曲康唑对NS-041药代动力学特征影响
[Translation] Evaluation of the effect of itraconazole on the pharmacokinetic characteristics of NS-041 in healthy Chinese adults
CTR20241102
评价NS-041在健康成年人中随机、双盲、安慰剂对照的单次剂量递增（SAD）和多次剂量递增（MAD）及食物影响（FE）的I期临床研究
[Translation] A randomized, double-blind, placebo-controlled, single-ascending dose (SAD) and multiple-ascending dose (MAD) and food effect (FE) Phase I clinical study of NS-041 in healthy adults
100 Clinical Results associated with NS-041
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100 Translational Medicine associated with NS-041
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100 Patents (Medical) associated with NS-041
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100 Deals associated with NS-041
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Seizures | Phase 2 | China | 18 Jun 2025 | |
| Epilepsy | Phase 1 | China | 19 Apr 2024 | |
| Depressive Disorder, Major | Phase 1 | - | - | |
| Mood Disorders | Phase 1 | China | - | |
| Pain | Phase 1 | China | - | |
| Depressive Disorder | Preclinical | China | 19 Jul 2024 | |
| Schizophrenia | Preclinical | China | 27 Sep 2023 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
CTR20241102 (NEWS) Manual  | Phase 1 | - | cjzxjfkmvh(smgxqysadk) = 该研究探索了5个剂量的单次给药和3个剂量的多次给药，结果展示出良好的安全性和药代动力学特征。项目组目前在进行统计分析和报告撰写，并积极为II期临床试验做准备。 pimpkzxqne (nwwwzycamr ) | Positive | 14 Nov 2024 |
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