Last update 21 Nov 2024

NS-041

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
Kv7.2 x Kv7.3
Mechanism
Kv7.2 agonists(Voltage-gated potassium channel subunit Kv7.2 agonists), Kv7.3 stimulants(Potassium voltage-gated channel subfamily KQT member 3 stimulants)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication
EpilepsyDepressive Disorder, MajorDepressive Disorder+ [1]
Inactive Indication-
Originator Organization
NeuShen Therapeutics (Shanghai) Co., Ltd.
Active Organization
NeuShen Therapeutics (Shanghai) Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with NS-041
CTR20241102 / RecruitingPhase 1
评价NS-041在健康成年人中随机、双盲、安慰剂对照的单次剂量递增（SAD）和多次剂量递增（MAD）及食物影响（FE）的I期临床研究
[Translation] A randomized, double-blind, placebo-controlled, single-ascending dose (SAD) and multiple-ascending dose (MAD) and food effect (FE) Phase I clinical study of NS-041 in healthy adults
100 Clinical Results associated with NS-041
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100 Translational Medicine associated with NS-041
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100 Patents (Medical) associated with NS-041
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100 Deals associated with NS-041
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
EpilepsyPhase 1
CN
NeuShen Therapeutics (Shanghai) Co., Ltd.
19 Apr 2024
Depressive Disorder, MajorPhase 1-
NeuShen Therapeutics (Shanghai) Co., Ltd.
-
Depressive DisorderPreclinical
CN
NeuShen Therapeutics (Shanghai) Co., Ltd.
19 Jul 2024
SchizophreniaPreclinical
CN
NeuShen Therapeutics (Shanghai) Co., Ltd.
27 Sep 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
CTR20241102 (NEWS)
ManualManual
Phase 1
Epilepsy
-
(goesidzfzh) = 该研究探索了5个剂量的单次给药和3个剂量的多次给药，结果展示出良好的安全性和药代动力学特征。项目组目前在进行统计分析和报告撰写，并积极为II期临床试验做准备。 cdjbvslkxp (ygcjowaoui )
Positive
14 Nov 2024
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Approval

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Regulation

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