Recent Analysis on Amyotrophic Lateral Sclerosis Clinical Trials

22 Feb 2021
www.globenewswire.com
Gene TherapymRNA
Los Angeles, USA, Feb. 22, 2021 (GLOBE NEWSWIRE) -- Recent Analysis on Amyotrophic Lateral Sclerosis Clinical Trials DelveInsight reports a complete review on Current and Emerging Therapies in the Amyotrophic Lateral Sclerosis pipeline enriched through the genetic breakthroughs along with recent discoveries in the field of stem-cell/gene therapy as well as molecular pathology. DelveInsight’s “Amyotrophic Lateral Sclerosis (ALS) Pipeline Insight'' report provides comprehensive insights about 160+ companies and 160+ pipeline drugs in the Amyotrophic Lateral Sclerosis pipeline landscapes. It comprises ALS pipeline drug profiles, including clinical and non-clinical stage products. It also includes the Amyotrophic Lateral Sclerosis therapeutics assessment by product type, stage, route of administration, and molecule type and further highlights the inactive ALS pipeline products.   Some of the significant features of the Amyotrophic Lateral SclerosisLateral Sclerosis Pipeline Report Get an overview of pipeline landscape @ Amyotrophic Lateral Sclerosis Clinical Trial AnalysisAmyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a group of disorders known as motor neuron diseases. It is characterized by the progressive degeneration and death of nerve cells in the brain and spinal cord, eventually that aid in communication between the nervous system and voluntary muscles of the body. It affects both the upper and lower motor neurons that interrupt the transmission. There is no cure for ALS. However, treatments available can help control symptoms, prevent unnecessary complications, and make living with the disease easier. Many pharmaceuticals companies are developing therapies that are focused on novel approaches to treat Amyotrophic Lateral Sclerosis. ALS Emerging Drugs Autologous MSC-NTF cells are being developed by BrainStorm Cell Therapeutics for ALS treatment. BrainStorm is recently enrolling a phase III pivotal trial using repeat-administration of autologous MSC-NTF cells in ALS at six leading clinical sites in the United States, backed by a grant from the California Institute for Regenerative Medicine. Pegcetacoplan is an investigational, targeted C3 therapy designed to regulate excessive activation of the complement cascade. Apellis plans to commence a clinical trial to comprehend if targeting C3 with pegcetacoplan may have the potential to slow the ALS progression by reducing the inflammation that causes motor neuron death. It is currently in the phase II stage of development. BIIB078 targets specific messenger RNA emerging from the C9orf72 gene and deteriorates it, eliminating the RNA and prohibiting the abnormal protein production it encodes. Importantly, BIIB078 largely preserves the normal C9orf72 protein emerging from the gene. It is currently in the phase I stage of development. ALS-205 is a potent antagonist of the human C5a1 receptor with no activity at the C5a2 receptor. It binds to the human C5a1 receptor on white blood cells and is a functional insurmountable antagonist. ALS-205 has displayed similar effects on other cell types, comprising lymphocytes, monocytes, and monocyte-derived macrophages. It is currently in the preclinical stage of development. For further product profiles, request @ ALS Pipeline TherapeuticsScope of Amyotrophic Lateral Sclerosis Pipeline Drug Insight Key Questions regarding Current Amyotrophic Lateral Sclerosis Treatment Landscape and Emerging Therapies Answered in the Pipeline Report Table of Contents Get customized pipeline report @ ALS Drugs Pipeline Report Related Reports DelveInsight' s Amyotrophic lateral sclerosis (ALS) - Market Insights, Epidemiology and Market Forecast - 2030 report provides a detailed overview of the disease and a depth understanding of historical and forecasted epidemiology. DelveInsight's Amyotrophic lateral sclerosis (ALS) - Epidemiology Forecast 2030 report delivers an in-depth understanding of the disease, historical, and forecasted epidemiology of Amyotrophic lateral sclerosis (ALS) in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan. Amyotrophic Lateral Sclerosis Market Insights, Competitive Landscape and Market Forecast-2025 report delivers an in-depth understanding of Amyotrophic Lateral Sclerosis. DelveInsight’s ‘Marfan Syndrome- Market Insights, Epidemiology and Market Forecast– 2030’ report delivers a full understanding of the Marfan Syndrome, historical and forecasted epidemiology. DelveInsight’s ‘Partial Paralysis Market Insights, Epidemiology and Market Forecast– 2030’ report delivers a full understanding of historical and forecasted epidemiology. Echocardiography Devices Market Insights, Competitive Landscape and Market Forecast-2025 report delivers an in-depth understanding of Echocardiography Devices. DelveInsight's Chronic Progressive Multiple Sclerosis - Market Insights, Epidemiology and Market Forecast - 2030 report provides a detailed overview of the disease and a depth understanding of historical and forecasted epidemiology. DelveInsight's Diffuse cutaneous systemic sclerosis (dcSSc) - Market Insights, Epidemiology and Market Forecast - 2030 report provides a detailed overview of the disease and a depth understanding of historical and forecasted epidemiology. DelveInsight's Multiple Sclerosis- Market Insights, Epidemiology, and Market Forecast - 2030 report provides a detailed understanding of historical and forecasted epidemiology. About DelveInsightDelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing end to end comprehensive solutions to improve their performance.
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