May 18, 2026 -- USA News Group News Commentary — For more than two decades, B7-H3 sat on the shortlist of theoretically perfect cancer drug targets that nobody could quite figure out how to hit. The protein is broadly overexpressed across some of the most common — and most lethal — solid tumors, including prostate, lung, breast, ovarian, head and neck, and pancreatic cancers. It is largely absent from healthy tissue. It correlates with poor prognosis. On paper, it has every quality a drug develo

Researchers at the Marshall University Joan C. Edwards School of Medicine have uncovered new evidence that tiny particles created in the gut may contribute to inflammation and chronic diseases linked to aging. The findings provide fresh insight into the connection between gut health, metabolism, immune function, and even sleep-related biological stress. The study, published in Aging Cell, focused on gut luminal exosomes, microscopic particles that cells use to communicate by carrying proteins a

Abstract includes previously reported data: cumulative MMR rate of 47% with 38% of patients achieving MMR by 24 weeks in mature, heavily pretreated 80 mg QD Phase 1b cohort In patients who previously received asciminib, cumulative MMR rate was 52%, with 38% of patients achieving MMR by 24 weeks ELVN-001 maintained a favorable safety and tolerability profile with 141 patients enrolled and a median treatment duration of ~32 weeks EHA presentation will include updated data with additional patients

12-month results from Part A of LIGHTHOUSE Trial reinforce ATSN-201's favorable safety pro durable structural and functional benefits in patients with X-linked retinoschisis Three-year data from Phase 1/2 trial confirm durable efficacy and tolerability of ATSN-101 in patients with Leber congenital amaurosis type 1 Atsena is advancing ATSN-201 and ATSN-101 into pivotal clinical trials in 2026 May 07, 2026 -- Atsena Therapeutics, a clinical-stage gene therapy company focused on using the life-cha

Pfizer has pulled the plug on an early-stage PD-L1 program as it looks to refine its cancer strategy after a series of encouraging readouts and high-value deals in recent months. The asset, dubbed PF-08046037, was being evaluated in a Phase 1 study, which combined the drug with sasanlimab, another investigational cancer therapy. Pfizer was testing the doublet against a variety of advanced or metastatic cancers, including non-small cell lung cancer, pancreatic ductal adenocarcinoma, and head and

April 21, 2026 -- Circulating white blood cells called neutrophils are some of the immune system's first responders. Their numbers shoot up during infection and inflammation, shifting the ratio of neutrophils to other types of immune cells in the blood. This ratio, called the neutrophil to lymphocyte ratio (NLR), is easily obtained from a complete blood cell count, which is used by clinicians to diagnose infection and other immune conditions. Now, a new study led by researchers at NYU Langone

ADCE-T02, a potential best-in-class Tissue Factor targeted antibody-drug conjugate (ADC), enters cohort expansion portion of the Tiffany-01 study in advanced solid tumors Two ADCE-T02 publications highlighting important preclinical results at the 2026 AACR Annual Meeting ADCE-D01, a first-in-class uPARAP targeted ADC, granted Orphan Drug Designation by the U.S. Food and Drug Administration (FDA) First patient dosed in Phase I trial of ADCE-B05, an ADC directed against an undisclosed first-in-cla

April 17, 2026 -- The Parker Institute for Cancer Immunotherapy (PICI), today announced that research and expertise from across its network will be showcased at the American Association for Cancer Research Annual Meeting, taking place April 17- 22 in San Diego, California. PICI leaders, investigators, and collaborators are contributing to nearly 100 posters, presentations, and discussions throughout the program - demonstrating the depth and breadth of the network's contributions to the field of

A New Hope for Patients with Advanced Gastric and Pancreatic Cancers April 9, 2026 -- A groundbreaking new CAR-T cell therapy for advanced gastrointestinal cancers is expected to become available in China in the first half of 2026, marking a major step forward in cancer treatment. Jiahui International Cancer Center will be among the leading medical institutions offering access to this innovative therapy for eligible patients. The therapy, known as satri-cel (CT041), is the world's first CAR-T

April 3, 2026 -- OneCyte, a leader in high-throughput single-cell analysis and cell line development technologies, and Kemp Proteins, a pioneer in protein engineering and expression solutions, today announced a strategic partnership to deliver industry-leading cell line development services for biopharmaceutical companies worldwide. This collaboration brings together OneCyte's proprietary single-cell platform for high-throughput, high-sensitivity, and high-speed clone selection with Kemp Protein