Beijing Tri-Prime Gene Pharmaceutical Co. Ltd.

To evaluate the safety, tolerability, pharmacokinetic (PK) and pharmacodynamic (PD) characteristics of multiple doses of a novel integrated interferon mutant injection of polyethylene glycol in healthy adult subjects and patients with chronic hepatitis B, and to provide a theoretical basis for the dosing regimen of subsequent clinical trials.

To evaluate the safety, tolerability, and pharmacokinetic (PK)/pharmacodynamic (PD) characteristics of a single dose of a novel integrated interferon mutant injection containing polyethylene glycol in healthy adult subjects, and to provide a theoretical basis for the dosing regimen of subsequent clinical trials.

To evaluate the efficacy and safety of nebulized recombinant human interferon α1b (IFNα1b) in the treatment of respiratory syncytial virus lower respiratory tract infections (pneumonia, bronchiolitis) in children