Last update 08 May 2025
River 2 Renal Corp.

River 2 Renal Corp.

Private Company|2020|New York, United States

Overview

Basic Info

Introduction
River 2 Renal Corp., a creator of innovative treatments aimed at eradicating rare diseases, was founded on October 27, 2020. Presently, the company's status is listed as Inactive. River 2 Renal Corp. ceased operations on January 26, 2023, after actively running for a period of two years, two months, and thirty days from the time it was set up till its closure.

Tags

Digestive System Disorders
Cardiovascular Diseases
Urogenital Diseases
Synthetic peptide

Disease domain score
A glimpse into the focused therapeutic areas
no Data
No Data
Technology Platform
Most used technologies in drug development
Targets
Most frequently developed targets
Top 5 Drug TypeCount
Synthetic peptide1
Top 5 TargetCount
RXFP1(Relaxin receptor 1)1

Related

1
Drugs associated with River 2 Renal Corp.
R2R01
Target
RXFP1
Mechanism
RXFP1 agonists
Active Org.
River 2 Renal Corp.River 2 Renal Corp. [+1]
Originator Org.
River 2 Renal Corp.River 2 Renal Corp.
Active Indication
Heart Failure [+4]
Inactive Indication-
Drug Highest PhasePhase 2
First Approval Ctry. / Loc.-
First Approval Date-
3
Clinical Trials associated with River 2 Renal Corp.
NCT06264310
/ CompletedPhase 2
A Phase 2, Double-Blind, Placebo-Controlled, Dose Range Finding Study to Assess Safety, Tolerability, Efficacy and Pharmacokinetics of the Relaxin Agonist R2R01 Combined With Standard of Care Versus Standard of Care Alone in Outpatients With Worsening Heart Failure (WHF)
NCT05875948
/ RecruitingPhase 2
A Single-blind, Phase 2, Multi-center, Randomized Study to Assess Safety, Tolerability, Efficacy and Pharmacokinetics of the R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome - Acute Kidney Injury
NL-OMON51081
/ CompletedNot Applicable
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Ranging Study in Healthy Volunteers to Assess Safety, Tolerability, and Evaluate the Pharmacokinetics and Pharmacodynamics of R2R01 - Placebo-controlled SAD/MAD of R2R01
100 Clinical Results associated with River 2 Renal Corp.
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0 Patents (Medical) associated with River 2 Renal Corp.
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100 Deals associated with River 2 Renal Corp.
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100 Translational Medicine associated with River 2 Renal Corp.
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Pipeline

Pipeline Snapshot as of 19 Aug 2026

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3
Phase 2 Clinical
1
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Current Projects

Drug(Targets)IndicationsGlobal Highest Phase
R2R01
 ( RXFP1 )		Acute Kidney Injury
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Phase 2
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