Synonyms leucine-rich repeat-containing G protein-coupled receptor 7, Leucine-rich repeat-containing G-protein coupled receptor 7, LGR7 + [5] |
Introduction Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. |
Target |
Mechanism RXFP1 agonists |
Active Org.- |
Originator Org. |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. RU |
First Approval Date01 Jan 2015 |
Target |
Mechanism RXFP1 agonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhasePhase 2 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Target |
Mechanism RXFP1 agonists |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhasePhase 2 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Start Date10 Jun 2024 |
Sponsor / Collaborator |
Start Date13 Feb 2024 |
Sponsor / Collaborator |
Start Date15 Jan 2023 |
Sponsor / Collaborator AstraZeneca PLC [+1] |